User:Steven J. Koch/MTC/March 31 2011

• Eisen paper--alert / invite to rate!
  • http://www.plosone.org/rate/getArticleRatings.action?articleURI=info%3Adoi%2F10.1371%2Fjournal.pone.0018011
  • Blog description: http://phylogenomics.blogspot.com/2011/03/story-behind-story-of-my-new-plosone.html
• Quiz
  • Raise right hand if bonds seem stronger when pulled slower
  • Raise left hand if bond strength does not depend very much on force
  • Raise both hands if bonds seem stronger when pulled faster
• Show figure from PRL
  • See Mendeley Paper, Koch 2003
  • Group discussion, osmotic pressure?
• Nucleosome unravelling data
  • Nucleosome popping paper: http://people.ccmr.cornell.edu/~mwang/papers/2002_PNAS_99-1752_Brower%20et%20al.pdf
  • Nucleosome structure: http://www.nap.edu/openbook.php?record_id=11001&page=52
  • Description of experiment
  • Quiz
    • Which bonds will break first? Weaker / Stronger / Doesn't matter
  • Partner Quiz: Which bonds are which in the figure?
  • Titin example -- explain AFM (page 6)
  • See Mendeley paper, Evans 2001 Annual Review
• Evans data example
  • What is up with the gray data points?