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Ph.D. in Biochemistry: University of Texas at Austin, August 2006
B.S in Chemistry: Penn State University, December 1999
Postdoctoral Associate, Aug. 2006 – present. Manalis Lab, MIT. Biosensor development
Graduate Student, Sept. 2000 – July 2006 Ellington Lab, UT Austin. In vitro ribozyme selection and characterization, biosensor development
Undergraduate Research, Sept. 1997 – Aug. 2000 Bevilacqua Lab, Penn State University. RNA structure / function
Knudsen SM, Lee J, Ellington AD, Savran CA. 2006. Ribozyme-mediated signal augmentation on a mass-sensitive biosensor. J Am Chem Soc 128: 15936-15937.
Garibotti AV, Knudsen SM, Ellington AD, Seeman NC. 2006. Functional DNAzymes organized into two-dimensional arrays. Nano Lett 6:1505-1507.
Knudsen SM, Ellington AD. 2006. Aptazymes: Allosteric Ribozymes and Deoxyribozymes as Biosensors. In: Klussmann S, ed. The Aptamer Handbook: Wiley-VCH. pp 290-309.
Bayer TS, Booth LN, Knudsen SM, Ellington AD. 2005. Arginine-rich motifs present multiple interfaces for specific binding by RNA. RNA 11:1848-1857.
Knudsen SM, Ellington AD. 2004. Ribozyme deja vu. Nat Struct Mol Biol 11:301-303.
Savran CA, Knudsen SM, Ellington AD, Manalis SR. 2004. Micromechanical detection of proteins using aptamer-based receptor molecules. Anal Chem 76:3194-3198.
Knudsen SM, Robertson MP, Ellington AD. 2004. In vitro selection of ribozymes dependent on peptides for activity. RNA 10:114-127.
Hesselberth JR, Robertson MP, Knudsen SM, Ellington AD. 2003. Simultaneous detection of diverse analytes with an aptazyme ligase array. Anal Biochem 312:106-112.
Thompson KM, Syrett HA, Knudsen SM, Ellington AD. 2002. Group I aptazymes as genetic regulatory switches. BMC Biotechnol 2:21.
Knudsen SM, Robertson MP, Ellington AD. 2001. In vitro selection using modified or unnatural nucleotides. In: Beaucage SL, Bergstrom DE, Glick GD, Jones RA, eds. Current Protocols in Nucleic Acid Chemistry. New York: John Wiley and Sons, Inc. pp 9.6.1-9.6.21.
Chadalavada DM, Knudsen SM, Nakano S, Bevilacqua PC. 2000. A role for upstream RNA structure in facilitating the catalytic fold of the genomic hepatitis delta virus ribozyme. J Mol Biol 301:349-367.