User:Sheldon Park

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I work in the Department of Chemical and Biological Engineering at the University at Buffalo (SUNY). My research interest is to understand the structural basis of protein function. Once the structure-function relationship has been modeled, we validate the model by designing novel sequences consistent with the target function and implementing the designs experimentally.


  • Ph.D, Harvard University
  • MS, MIT
  • BA, UC Berkeley

Research interests

  • Streptavidin
  • MDM2-p53
  • Bax
  • GPCR
  • Posttranslational modification

Selected Publications

  1. Park, S., Yang, X., Saven, J.G. Advances in Computational Protein Design, Curr Op in Struct Biol (2004) pmid=15313244
  2. Park, S., Saven, J.G. Statistical and molecular dynamics studies of buried waters in globular proteins, Proteins (2005) pmid=15937899
  3. Szep, S., Park, S., Boder, E.T., Van Duyne, G., Saven, J.G. Structural coupling between FKBP12 and buried water, Proteins (2009) pmid=18704951


  1. Park, S.J. and Cochran, J.R. Protein Engineering and Design, CRC Press/Taylor & Francis (due summer 2009)

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