User:Sean C. Sleight

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Sean C. Sleight (an artistic interpretation)

I'm a postdoc in Herbert Sauro's lab at University of Washington. I am working on a synthetic biology project and am an advisor for the UW iGEM team.


  • 2007, PhD, Michigan State University, Microbiology and Molecular Genetics
  • 1999, BS, University of Arizona, Molecular and Cellular Biology

Research interests

  1. Synthetic biology
  2. Experimental and directed evolution
  3. Mutation rates under stress


  • Sleight S.C., C. Orlic, D. Schneider, and R.E. Lenski

Genetic basis of evolutionary adaptation by Escherichia coli to stressful cycles of freezing, thawing and growth. 2008. Genetics Sep;180(1):431-43.

  • Sleight S.C. and R.E. Lenski

Evolutionary adaptation to freeze-thaw-growth cycles in Escherichia coli. 2007. Physiological and Biochemical Zoology 80(4): 370-385.

  • Sleight S.C., N.S. Wigginton, and R.E. Lenski

Increased susceptibility to repeated freeze-thaw cycles in Escherichia coli following long-term evolution in a benign environment. 2006. BMC Evolutionary Biology 6: 104 [8 pp].

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