User:Scott P. Tarone

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Contact Info

Scott P. Tarone (an artistic interpretation)

• Scott P. Tarone
• www.synapticsynthase.com
• Email me through OpenWetWare

I am an independent researcher, self-taught in the biosciences with a focus on Immunology and Targeted Cancer Therapies. I proposed a targeted cancer therapeutic in a paper that was published in Drug Discovery Today.(http://www.sciencedirect.com/science/article/pii/S1359644615000653).

Currently I am teaching myself computational chemistry; specifically protein and small molecule therapeutic design.

Education

• Year, PhD, Institute
• Year, MS, Institute
• Year, BS, Institute

Research interests

1. Interest 1
2. Interest 2
3. Interest 3

Publications

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Intracellular Caspase-Modulating Chimeric Antigen Receptor

• Intracellular agent targets mutant proteins and induces apoptosis.
• Chimera with a targeting domain, a molecular switch and a pro-apoptotic effector.
• A constitutively active caspase-3 mutant (V266E), efficient at low concentrations.
• Engineered mAb or zinc finger targeting tumor-specific mutations.
• Inteins provide flexible platform for control of protein function.

Useful links

• Introductory tutorial
• OpenWetWare help pages