User:Nico Jehmlich
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Contact Info
- Nico Jehmlich
- Helmholtz Centre for Environmental Research - UFZ
- Department of Proteomics
- Permoserstr. 15
- 04318 Leipzig, Germany
- Email me through OpenWetWare
I work in the Department of Proteomics at the Helmholtz Centre for Environmental Research - UFZ.
The purpose of my work is the development of a new strategy to describe microbial communities in anaerobic mixed cultures. The description of the functional biodiversity plays an important role in clarifying functions of microorganisms within a community. The new strategy is based on the combination of Flow Cytometry and Metaproteom analysis.
The multi-parametric Flow Cytometry is used to find active subpopulations due to basic physical and molecular characteristics of the cells. Subsequently, the proteom of the sorted subpopulations will be analyzed and consequently the function of microorganisms will be assigned.
Education
- since Oct 2006, PhD, Helmholtz Centre for Environmental Research - UFZ
- 2006, Diploma, Helmholtz Centre for Environmental Research - UFZ
- 2001 - 2005, Biology student at the University of Leipzig
- 2000, BS, Thomasschule, Leipzig
Research interests
- Investigation of the function and structure of microbial communities
- Metabolic labeling by stable isotope probing (Protein-SIP)
- Human associated microorganisms such as Lactobacillus
Publications
- Jehmlich N, Schmidt F, Hartwich M, von Bergen M, Richnow HH, and Vogt C. Incorporation of carbon and nitrogen atoms into proteins measured by protein-based stable isotope probing (Protein-SIP). Rapid Commun Mass Spectrom. 2008 Sep;22(18):2889-97. DOI:10.1002/rcm.3684 |
- Jehmlich N, Schmidt F, von Bergen M, Richnow HH, and Vogt C. Protein-based stable isotope probing (Protein-SIP) reveals active species within anoxic mixed cultures. ISME J. 2008 Nov;2(11):1122-33. DOI:10.1038/ismej.2008.64 |
- Johannes J, Bluschke A, Jehmlich N, von Bergen M, and Boll M. Purification and characterization of active-site components of the putative p-cresol methylhydroxylase membrane complex from Geobacter metallireducens. J Bacteriol. 2008 Oct;190(19):6493-500. DOI:10.1128/JB.00790-08 |
- Martin C, Pecyna M, Kellner H, Jehmlich N, Junghanns C, Benndorf D, von Bergen M, and Schlosser D. Purification and biochemical characterization of a laccase from the aquatic fungus Myrioconium sp. UHH 1-13-18-4 and molecular analysis of the laccase-encoding gene. Appl Microbiol Biotechnol. 2007 Dec;77(3):613-24. DOI:10.1007/s00253-007-1207-2 |
- Thiele B, Rieder O, Jehmlich N, von Bergen M, Müller M, and Boll M. Aromatizing cyclohexa-1,5-diene-1-carbonyl-coenzyme A oxidase. Characterization and its role in anaerobic aromatic metabolism. J Biol Chem. 2008 Jul 25;283(30):20713-21. DOI:10.1074/jbc.M802841200 |
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Kellner H, Jehmlich N, Benndorf D, Hoffmann R, Rühl M, Hoegger PJ, Majcherczyk A, Kües U, von Bergen M, and Buscot F
Detection, quantification and identification of fungal extracellular laccases using polyclonal antibody and mass spectrometry
Enzyme and Microbial Technology (2007) 41:694–701 doi:10.1016/j.enzmictec.2007.06.002
