User:Michael A. Tarselli

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Contact Info

Mike Tarselli, organic chemist
  • Michael A. Tarselli
  • Biomedisyn Corp.
  • USA
  • mtarselli_AT_biomedisyn.com

I work as a Principal Scientist at Biomedisyn Corp. I learned about OpenWetWare from Mat, Murray, and Katrina at the University of Syndney, and I've joined to help write the Catalytic, Asymmetric Pictet-Spengler review.

Education

  • 2010, Postdoc, The Scripps Research Institute-Florida
  • 2009, CCLI Fellow, University of Washington-Seattle
  • 2008, PhD, University of North Carolina-Chapel Hill
  • BA Honors, University of Massachusetts-Amherst

Research interests

  1. Medicinal Chemistry
  2. Alkaloids
  3. New metal-catalyzed methodology
  4. Enzymatic Catalysis

Publications

  1. Tarselli MA, Raehal KM, Brasher AK, Streicher JM, Groer CE, Cameron MD, Bohn LM, and Micalizio GC. Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain. Nat Chem. 2011 Jun;3(6):449-53. DOI:10.1038/nchem.1050 | PubMed ID:21602859 | HubMed [Paper1]
  2. Chen MZ, McLaughlin M, Takahashi M, Tarselli MA, Yang D, Umemura S, and Micalizio GC. Preparation of stereodefined homoallylic amines from the reductive cross-coupling of allylic alcohols with imines. J Org Chem. 2010 Dec 3;75(23):8048-59. DOI:10.1021/jo101535d | PubMed ID:21069994 | HubMed [Paper2]
  3. Tarselli MA and Micalizio GC. Aliphatic imines in titanium-mediated reductive cross-coupling: unique reactivity of Ti(O-i-Pr)4/n-BuLi. Org Lett. 2009 Oct 15;11(20):4596-9. DOI:10.1021/ol901870n | PubMed ID:19810765 | HubMed [Paper3]
  4. Tarselli MA, Zuccarello JL, Lee SJ, and Gagné MR. Gold(I)-catalyzed cascade cyclization of allenyl epoxides. Org Lett. 2009 Aug 6;11(15):3490-2. DOI:10.1021/ol901391s | PubMed ID:19588972 | HubMed [Paper4]
  5. Weber D, Tarselli MA, and Gagné MR. Mechanistic surprises in the gold(I)-catalyzed intramolecular hydroarylation of allenes. Angew Chem Int Ed Engl. 2009;48(31):5733-6. DOI:10.1002/anie.200902049 | PubMed ID:19562821 | HubMed [Paper5]
  6. Tarselli MA, Liu A, and Gagné MR. Gold(I)-catalyzed intermolecular hydroarylation of allenes with nucleophilic arenes: scope and limitations. Tetrahedron. 2009 Feb;65(9):1785-1789. DOI:10.1016/j.tet.2008.10.110 | PubMed ID:21512612 | HubMed [Paper6]
  7. Tarselli MA and Gagné MR. Gold(I)-catalyzed intramolecular hydroarylation of allenes. J Org Chem. 2008 Mar 21;73(6):2439-41. DOI:10.1021/jo7024948 | PubMed ID:18278940 | HubMed [Paper7]
  8. Tarselli MA, Chianese AR, Lee SJ, and Gagné MR. Gold(I)-catalyzed asymmetric cycloisomerization of eneallenes into vinylcyclohexenes. Angew Chem Int Ed Engl. 2007;46(35):6670-3. DOI:10.1002/anie.200701959 | PubMed ID:17661298 | HubMed [Paper8]
All Medline abstracts: PubMed | HubMed