User:Md. Badrul Arefin

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Over-expression of GFP fused protein in Drosophila melanogaster)
  • Md. Badrul Arefin
  • Postdoatoral Researcher at Prof. Stefan Thor lab, Linköping University, Sweden
  • Former Postdoctoral Researcher, Stockholm University
  • email: badrul.arefin@liu.se
  • Website (new): https://sites.google.com/site/mdbadrularefin/


By training, I am a molecular and developmental biologist. I have defended my PhD thesis in molecular biology titled ‘molecular characterization of the Drosophila responses towards nematodes’ on 24th of November 2016. My PhD thesis work at Prof. Ulrich Theopold lab in Stockholm University was to characterize the host-pathogen interactions at a molecular and cellular level using Drosophila-nematode model. My core expertise lies mostly in cell and molecular biology.

Education & Employment

  • May 2017-present: Postdoatoral Researcher at Prof. Stefan Thor lab, Linköping University, Sweden
  • Dec 2016-March 2017: Postdoctoral fellow at Stockholm University
  • 2012-2016: PhD student, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University
  • 2010-2012: Stipend student: Developmental Biology, The Wenner-Gren Institute, Stockholm University
  • 2008-2010: M. Sc in Biotechnology, Lund University, Sweden
  • 2001-2006: B. Sc in Biotechnology & Genetic Engineering, Khulna University, Bangladesh

Research interest

I am deeply passionate about to understand the mysteries of life at a molecular and cellular level. Most of my research involves Drosophila melanogaster, an excellent model organism in biology.

Research experiences

  • PhD research: Molecular characterization of the Drosophila responses towards nematodes.Supervisor: Prof. Ulrich Theopold, Molecular Biosciences, Stockholm University (SU), Sweden.
  • Licentiate thesis (M.Phil equivalent): The Drosophila defense towards nematodes and the contribution of danger signals. Supervisor: Prof. Ulrich Theopold, Molecular Biosciences, SU.
  • Stipend project: Identification of apical secretion pathways in epithelial tube morphogenesis. Supervisor: Prof. Christos Samakovlis, Developmental Biology, SU.
  • Master thesis: Analysis of the mechanism of bicoid mRNA transport and the function of a Bicoid isoform. Supervisor: Prof. Stefan Baumgartner, Developmental Biology, Lund University, Sweden.

Teaching experience/lab supervision at Stockholm University

  • Molecular Cell Biology course lab, undergraduate level, 2015, 2014, 2013 & 2012.
  • Molecular Genetics course lab, Masters level, 2014 & 2013.
  • I supervise 13 persons from Sweden and abroad on a daily basis from various levels including exchange PhD students, guest researcher, diploma project and master thesis students.
  • Completed a teaching course at Stockholm University: Introduction to teaching for postgraduate and postdoctoral researchers, 2015.

Talks

  • Oral presentation: Abstract was selected for talk (accommodate only 10-15%) at the 56th Annual Drosophila Research Conference (ADRC, the biggest Drosophila research conference), Chicago, USA, March 4-8, 2015.
  • Oral presentation at the crossroads between insect immunology, physiology and ecology, Brno, Czech Republic. Sept. 13-16, 2015
  • At Global Health Institute, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland, September 5th, 2016. Host: Prof. Bruno Lemaitre.
  • At Linköping University, Sweden, Department of Clinical and Experimental Medicine, Developmental Biology, Jan 19th, 2017. Host: Prof. Stefan Thor.

Professional contribution as a peer reviewer for

1) PLOS ONE, 2) Fly, 3) Insect Science, & 4) Insect Molecular Biology journal.

Publications

  • B. Arefin, L. Kucerova, P. Dobes et al., Genome-wide transcriptional analysis of Drosophila larvae infected by entomopathogenic nematodes shows involvement of complement, recognition and extracellular matrix proteins. J Innate Immun 6, 192-204 (2014). (Journal cover page)
  • B. Arefin, L. Kucerova, L, R. Krautz et al., Apoptosis in Hemocytes Induces a Shift in Effector Mechanisms in the Drosophila Immune System and Leads to a Pro-Inflammatory State. PloS One 10, e0136593 (2015).
  • L. Kucerova, V. Broz, B. Arefin et al., The Drosophila Chitinase-Like Protein IDGF3 Is Involved in Protection against Nematodes and in Wound Healing. J Innate Immun, (2015). (Journal cover page)
  • M. Kunc, B. Arefin, P. Hyrsl and U. Theopold. Monitoring the effect of pathogenic nematodes on locomotion of Drosophila larvae. Fly, (2017).
  • R. Krautz, B. Arefin, U. Theopold, Damage signals in the insect immune response. Front Plant Sci 5, 342 (2014).