User:Mateo
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Matthew Wallace Department of Chemistry wallacem@mit.edu
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Hello, I am Matt in the Lippard Lab at MIT.
Research Interests
- The biological mechanism behind cisplatin's anti-cancer properties
Education
2006 - Present: Postdoctoral Researcher, Bioinorganic Chemistry, MIT
2005: Ph.D., Biochemistry and Molecular Biology, University of California, Los Angeles (UCLA)
1999: B.S., Biochemistry, University of California, Davis (UC Davis)
Publications
- Sanchez RJ, Srinivasan C, Munroe WH, Wallace MA, Martins J, Kao TY, Le K, Gralla EB, and Valentine JS. Exogenous manganous ion at millimolar levels rescues all known dioxygen-sensitive phenotypes of yeast lacking CuZnSOD. J Biol Inorg Chem. 2005 Dec;10(8):913-23. DOI:10.1007/s00775-005-0044-y |
- Wallace MA, Bailey S, Fukuto JM, Valentine JS, and Gralla EB. Induction of phenotypes resembling CuZn-superoxide dismutase deletion in wild-type yeast cells: an in vivo assay for the role of superoxide in the toxicity of redox-cycling compounds. Chem Res Toxicol. 2005 Aug;18(8):1279-86. DOI:10.1021/tx050050n |
- Wallace MA, Liou LL, Martins J, Clement MH, Bailey S, Longo VD, Valentine JS, and Gralla EB. Superoxide inhibits 4Fe-4S cluster enzymes involved in amino acid biosynthesis. Cross-compartment protection by CuZn-superoxide dismutase. J Biol Chem. 2004 Jul 30;279(31):32055-62. DOI:10.1074/jbc.M403590200 |
- Lindsay LL, Wallace MA, and Hedrick JL. A hatching enzyme substrate in the Xenopus laevis egg envelope is a high molecular weight ZPA homolog. Dev Growth Differ. 2001 Jun;43(3):305-13. DOI:10.1046/j.1440-169x.2001.00577.x |
