User:Kelsic/Links/PQEReadingTimeline

Cell lineage interactions

Cancer stem cells

1. Polyak K and Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer. 2009 Apr;9(4):265-73. DOI:10.1038/nrc2620 |

   Cellular plasticity creates distinct tumor sub-populations and may influence malignant phenotypes

2. Baum B, Settleman J, and Quinlan MP. Transitions between epithelial and mesenchymal states in development and disease. Semin Cell Dev Biol. 2008 Jun;19(3):294-308. DOI:10.1016/j.semcdb.2008.02.001 |

   Molecular biology of Mesenchymal Epithelial Transition

Signaling

Development

3. Richards GS and Degnan BM. The dawn of developmental signaling in the metazoa. Cold Spring Harb Symp Quant Biol. 2009;74:81-90. DOI:10.1101/sqb.2009.74.028 |

   Comparative Genome analysis of Wnt, Notch, TGF-beta, and Hedgehog pathways

Biochemistry

4. Scott JD and Pawson T. Cell signaling in space and time: where proteins come together and when they're apart. Science. 2009 Nov 27;326(5957):1220-4. DOI:10.1126/science.1175668 |

   review of cell signaling protein motifs