User:Jarle Pahr/Degradation tags

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Cytoplasmic degradation of :

ClpAP and ClpXP degrade proteins with tags located in the interior of the primary sequence:

The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system.:

An Intrinsic Degradation Tag on the ClpA C-Terminus Regulates the Balance of ClpAP Complexes with Different Substrate Specificity

See also:

REVIEW Development and Use of Fluorescent Protein Markers in Living Cells:;300/5616/87.pdf

The SsrA-SmpB system for protein tagging, directed degradation and ribosome rescue.

Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA.

Turnover of Endogenous SsrA-tagged Proteins Mediated by ATP-dependent Proteases in Escherichia coli*[S with combining enclosing square]:

Overlapping recognition determinants within the ssrA degradation tag allow modulation of proteolysis:

A specificity-enhancing factor for the ClpXP degradation machine:

Flexible linkers leash the substrate binding domain of SspB to a peptide module that stabilizes delivery complexes with the AAA+ ClpXP protease.: