Notes and links regarding antibiotics:
ATCC Antibiotic concentration recommendations:
Degraded by B-lactamase (encoded by bla)
- Also degraded by B-lactamase, but slower than Ampicillin. (http://bitesizebio.com/articles/whats-the-problem-with-ampicillin-selection/)
- More expensive than ampicillin.
Capsule Formation is Necessary for Kanamycin Tolerance in Escherichia coli K12: http://www.microbiology.ubc.ca/sites/default/files/roles/drupal_ungrad/JEMI/17/05.1G.pdf
- Inhibits protein translation by interfering with peptide bond formation.
Designing Antibiotic Cycling Strategies by Determining and Understanding Local Adaptive Landscapes : http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056040
Persistence in the face of antibiotics:
Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules http://www.pnas.org/content/110/40/16169.abstract
The unstructured domain of colicin N kills Escherichia coli: http://onlinelibrary.wiley.com/doi/10.1111/mmi.12260/abstract