User:Ivan Baxter

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Ivan Baxter

Ivan Baxter
Research Computational Biologist
USDA Plant Genetics Research Unit &
Donald Danforth Plant Science Center
St Louis, Mo, USA

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About Me

I am interested in understanding how plants regulate the mobilization, uptake, translocation, and storage of elements in different environments.

The focus of our attempts to study this question is Ionomics. We analyze the elemental content of 500-1000 samples per week using ICP-MS. To make sense of the data coming off the machine, we also need to collect data about the environment the plants were grown in and how the samples were processed. To record all this information, control the workflows, and store and analyze the data, we created the Purdue Ionomics Information Management System (PiiMS). This system has helped the great ionomics team I work with to map several genes important for elemental accumulation in Arabidopsis thaliana. But to really answer this question we will also need to understand how all the genes/transcripts/proteins/metabolites interact to control the ionome (all of the mineral elements in a cell, tissue, or organism).

I am also the Plant Biology section editor of PLoS ONE and a big supporter of Open Access.

Here is my Facebook page.



My ResearcherID page

  1. Guerinot, ML, Baxter I, Salt DE. (2009) From the ionome to the genome: Identifying gene networks that control the mineral content of plants. In Plant Systems Biology. Coruzzi G and Gutierrez R, eds. Wiley Publishing. Link

  2. Baxter I. Ionomics: studying the social network of mineral nutrients. Curr Opin Plant Biol. 2009 Jun;12(3):381-6. DOI:10.1016/j.pbi.2009.05.002 | PubMed ID:19481970 | HubMed [Paper15]
  3. Baxter I, Hosmani PS, Rus A, Lahner B, Borevitz JO, Muthukumar B, Mickelbart MV, Schreiber L, Franke RB, and Salt DE. Root suberin forms an extracellular barrier that affects water relations and mineral nutrition in Arabidopsis. PLoS Genet. 2009 May;5(5):e1000492. DOI:10.1371/journal.pgen.1000492 | PubMed ID:19461889 | HubMed [Paper14]
  4. Danku J, Gumaelius L, Baxter I, Salt DE. (2009) A high-throughput method for Saccharomyces cerevisiae (yeast) ionomics. J. Anal. At. Spectrom., 24, 103 - 107,doi:10.1039/b803529f

  5. Baxter IR, Vitek O, Lahner B, Muthukumar B, Borghi M, Morrissey J, Guerinot ML, and Salt DE. The leaf ionome as a multivariable system to detect a plant's physiological status. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12081-6. DOI:10.1073/pnas.0804175105 | PubMed ID:18697928 | HubMed [Paper12]
  6. Baxter I, Muthukumar B, Park HC, Buchner P, Lahner B, Danku J, Zhao K, Lee J, Hawkesford MJ, Guerinot ML, and Salt DE. Variation in molybdenum content across broadly distributed populations of Arabidopsis thaliana is controlled by a mitochondrial molybdenum transporter (MOT1). PLoS Genet. 2008 Feb 29;4(2):e1000004. DOI:10.1371/journal.pgen.1000004 | PubMed ID:18454190 | HubMed [Paper11]
  7. Salt DE, Baxter I, and Lahner B. Ionomics and the study of the plant ionome. Annu Rev Plant Biol. 2008;59:709-33. DOI:10.1146/annurev.arplant.59.032607.092942 | PubMed ID:18251712 | HubMed [Paper10]
  8. Borevitz JO, Hazen SP, Michael TP, Morris GP, Baxter IR, Hu TT, Chen H, Werner JD, Nordborg M, Salt DE, Kay SA, Chory J, Weigel D, Jones JD, and Ecker JR. Genome-wide patterns of single-feature polymorphism in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12057-62. DOI:10.1073/pnas.0705323104 | PubMed ID:17626786 | HubMed [Paper9]
  9. Baxter I, Ouzzani M, Orcun S, Kennedy B, Jandhyala SS, and Salt DE. Purdue ionomics information management system. An integrated functional genomics platform. Plant Physiol. 2007 Feb;143(2):600-11. DOI:10.1104/pp.106.092528 | PubMed ID:17189337 | HubMed [Paper8]
  10. Baxter IR and Borevitz JO. Mapping a plant's chemical vocabulary. Nat Genet. 2006 Jul;38(7):737-8. DOI:10.1038/ng0706-737 | PubMed ID:16804534 | HubMed [Paper7]
  11. Rus A, Baxter I, Muthukumar B, Gustin J, Lahner B, Yakubova E, and Salt DE. Natural variants of AtHKT1 enhance Na+ accumulation in two wild populations of Arabidopsis. PLoS Genet. 2006 Dec 1;2(12):e210. DOI:10.1371/journal.pgen.0020210 | PubMed ID:17140289 | HubMed [Paper6]
  12. Hazen SP, Pathan MS, Sanchez A, Baxter I, Dunn M, Estes B, Chang HS, Zhu T, Kreps JA, and Nguyen HT. Expression profiling of rice segregating for drought tolerance QTLs using a rice genome array. Funct Integr Genomics. 2005 Apr;5(2):104-16. DOI:10.1007/s10142-004-0126-x | PubMed ID:15480887 | HubMed [Paper5]
  13. Baxter IR, Young JC, Armstrong G, Foster N, Bogenschutz N, Cordova T, Peer WA, Hazen SP, Murphy AS, and Harper JF. A plasma membrane H+-ATPase is required for the formation of proanthocyanidins in the seed coat endothelium of Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2649-54. DOI:10.1073/pnas.0406377102 | PubMed ID:15695592 | HubMed [Paper4]
  14. Baxter I, Tchieu J, Sussman MR, Boutry M, Palmgren MG, Gribskov M, Harper JF, and Axelsen KB. Genomic comparison of P-type ATPase ion pumps in Arabidopsis and rice. Plant Physiol. 2003 Jun;132(2):618-28. DOI:10.1104/pp.103.021923 | PubMed ID:12805592 | HubMed [Paper3]
  15. Vitart V, Baxter I, Doerner P, and Harper JF. Evidence for a role in growth and salt resistance of a plasma membrane H+-ATPase in the root endodermis. Plant J. 2001 Aug;27(3):191-201. DOI:10.1046/j.1365-313x.2001.01081.x | PubMed ID:11532165 | HubMed [Paper2]
  16. Hegmans A, Sabat M, Baxter I, Freisinger E, and Lippert B. Synthetic Ways to Tris(nucleobase) Complexes Derived from cis-Diammineplatinum(II) and a Platinum(II) Complex Containing Four Different Ligands, Three of Which Are Nucleobases. Inorg Chem. 1998 Sep 21;37(19):4921-4928. DOI:10.1021/ic9802193 | PubMed ID:11670657 | HubMed [Paper1]

All Medline abstracts: PubMed | HubMed

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