- aka Eremothecium Gossypii
- filamentous fungus
- 7 chromosomes, 9.2Mb
- 4718 protein coding genes (smallest genome of a free living eukaryote)
- Probably has the simplest version of the pheromone response pathway
- CG content 52%
- 95% of ORF have homologs in S. cerevisiae (4281 or 90% at syntenic positions)
- Protein sequence conservation between homologs 20-100% identity
- The hemiascomycete Ashbya gossypii was first described in 1929 as a cotton pathogen transmitted by sucking insects and has considerable commercial value as a major source for riboflavin (vitamin B2). Ashbya shows filamentous growth with multinucleated and extensively branching hyphae. A yeast-type growth has up to now not been observed.
- One way to examine essential yeast genes is to compare yeast with other free-living eukaryotic organisms that are syntenic but have smaller genomes. One such organism is Ashbya gossypii, a filamentous fungus with only seven chromosomes.