User:George M. Twaddle

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George M. Twaddle
  • George M. Twaddle
  • Ivy Tech Community College of Indiana - South Bend
  • 220 Dean Johnson Blvd
  • South Bend, IN 46601
  • gtwaddle AT ivytech DOT edu

I am one of five department chairs for biotechnology in the Ivy Tech Community College system. I learned about OpenWetWare from IGEM, and I've joined because I want to transcend paper lab notebooks and build bridges to the synthetic biology community. Our Program for Biotechnology is an example of a CC "PURE" or Program Undergraduate Research Experience and as a result there is an open ended research component in all of the laboratory classes. My lab is a founding partner of the Community College Undergraduate Research Initiative. . Every other year, funds permitting we entery the IGEM.


  • 1990, PhD, Univeristy of Chicago, Committee on Immunology a.b.d. (alas)
  • 2001, MS, Secondary Science Education, School of Education, Indiana University (South Bend)
  • 1980, BS, Biology, Purdue University

Research interests

  1. Synthetic biology, specifically the construction of biosensors for environmental contaminants (arsenic, coliphage, estrogen)
  2. Estrogen and cancer biology
  3. DNA barcoding and artificial selection


  1. Turbov JM, Twaddle GM, Yang X, Liu NM, and Murthy S. Effects of receptor tyrosine kinase inhibitor A47 on estrogen and growth factor-dependent breast cancer cell proliferation and apoptosis in vitro. J Surg Oncol. 2002 Jan;79(1):17-29. PubMed ID:11754373 | HubMed [Paper1]
  2. Twaddle GM, Turbov J, Liu N, and Murthy S. Tyrosine kinase inhibitors as antiproliferative agents against an estrogen-dependent breast cancer cell line in vitro. J Surg Oncol. 1999 Feb;70(2):83-90. PubMed ID:10084649 | HubMed [Paper2]
  3. pmid= [Paper3]
    leave a comment about a paper here
  4. isbn= [Book1]
All Medline abstracts: PubMed | HubMed

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