User:Etienne Robillard/Notebook/Hypercomputation

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Neuronal hypercomputation

Synaptic hypercomputation

The synaptic hypercomputation (SH) hypothesis states that the phase coherence of neural communication (synaptic latency) may emerges via long-range synchronicity in the gamma range. In specific, this neurocomputational model is controlled by synaptic (dopamine?) exocytosis, regulating phase-dependent presynaptic action potential (synaptic waveform) in a quantum system. [1]

In addition, the presynaptic (action potential) waveform is determined by the synaptic latency of coherent energy transfer in tubulin heterodimer. [2]

To summarize, the interneuronal superradiance and synchronicity of biophotonic quantum beats in tubulin heterodimer is evidence of phase-dependent synaptic hypercomputation driving advanced neurocomputational functions (quantum coherence) of the brain. [2][3]

Cannabimimetic hypercomputation

Endocannabinoid-mediated synaptic hypercomputation is caused by the pharmacological activation of cannabinoid receptors (CB1, CB2) controlling neuronal phase coherence (synchronized gamma oscillations) at (GABAergic?) interneuron networks. [4]

Anandamide-dopamine cross-talk:

  • Review: GPCR receptor heteromerization
    • Anandamide-dopamine heteromeric transactivation may potentiate synaptic hypercomputation in the gamma band. [5][6]
  • Fast synaptic inhibition by retrograde signaling may trigger synchronized gamma oscillations in the hippocampus. [6]

Neuroholographic hypercomputation

Imagination is more important than knowledge:

Research subtopics:

  • Tubulin heterodimerization dynamics

Photosynthetic hypercomputation

Quantum coherence in photosynthetic systems is evidence of biophotonic-like (coherent) energy transfer in plants mitochondria.

Neuronal phase coherence and synchronicity

Neuronal phase coherence is non-local "quantum-like" entanglement because long-range synchronicity is critical for optimal biophotonic communication in the gamma band. [7]

Notes

  • Synaptic binding (latency?) is a phase-dependent coherent effect of exocytosis?
  • Anandamide/dopamine cross-talk fine-tune synaptic binding of intracellular CB1 receptors?

Discussion

References

  1. http://www.sciencedirect.com/science/article/pii/S0896627315008235 [Paper1]
    Rhythms for Cognition: Communication through Coherence
  2. https://www.ncbi.nlm.nih.gov/pubmed/24070914 [Paper6]
    Consciousness in the universe: a review of the 'Orch OR' theory.
  3. http://iopscience.iop.org/article/10.1088/1742-6596/306/1/012075/meta [Paper4]
    Plausibility of quantum coherent states in biological systems
  4. https://www.ncbi.nlm.nih.gov/pubmed/17180162 [Paper7]
    Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks.
  5. http://molpharm.aspetjournals.org/content/67/5/1697.short [Paper2]
    Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Enhances Heterodimer Formation: A Mechanism for Receptor Cross-Talk?
  6. http://www.pnas.org/content/99/20/13222.full [Paper5]
    Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks
  7. http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003723 [Paper3]
    Phase-Coherence Transitions and Communication in the Gamma Range between Delay-Coupled Neuronal Populations
  8. https://www.ncbi.nlm.nih.gov/pubmed/14962620 [Paper8]
    Biophotons, microtubules and CNS, is our brain a "holographic computer"?
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978290/ [Paper9]
    Human high intelligence is involved in spectral redshift of biophotonic activities in the brain

See also