User:Deng-Ke Niu
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Contact Info
- Deng-Ke Niu
- College of Life Sciences, Beijing Normal University
- Xinjiekouwai Street 19
- Beijing, China.
- Email me through OpenWetWare
Education
- 1999, PhD, Wuhan University
- 1996, MS, Lanzhou University
- 1993, BS, Hebei University
- 2001-2003, Postdoc, Beijing Normal University
- 2000-2001, CNRS-University Paul Sabatier, Toulouse III
- 1999-2001, Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan
Research interests
- The origin and evolution of introns, including the possible costs and benefits of introns, the mechanisms of intron gain and intron loss
- Theoretical consideration on various problems. Propose hypotheses to remind other researchers the unnoticed possibilities.
Publications
- Niu D-K, Cao J-L (2010) Nucleosome deposition and DNA methylation may participate in the recognition of premature termination codon in nonsense-mediated mRNA decay. FEBS Lett. 584:3509-3512
- Li N, Lv J, Niu D-K (2009) Low contents of carbon and nitrogen in highly abundant proteins: Evidence of selection for the economy of atomic composition. J. Mol. Evol. 68:248-255
- Huang Y-F, Niu D-K (2008) Evidence against the energetic cost hypothesis for the short introns in highly expressed genes. BMC Evol. Biol. 8:154
- Niu DK (2008) Exon definition as a potential negative force against intron losses in evolution. Biol. Direct 3:46
- Lv J, Li N, Niu D-K (2008) Association between the availability of environmental resources and the atomic composition of organismal proteomes: Evidence from Prochlorococcus strains living at different depths. Biochem. Biophys. Res. Commun. 375:241-246
- Wang HF, Hou WR, Niu DK (2008) Strand compositional asymmetries in vertebrate large genes. Mol. Biol. Rep. 35:163-169
- Niu D-K (2007) Protecting exons from deleterious R-loops: a potential advantage of having introns. Biol. Direct 2:11
- Li S-W, Feng L, Niu D-K (2007) Selection for the miniaturization of highly expressed genes. Biochem. Biophys. Res. Commun. 360:586-592
- Wang H-F, Feng L, Niu D-K (2007) Relationship between mRNA stability and intron presence. Biochem. Biophys. Res. Commun. 354:203-208
- Feng L, Niu D-K (2007) Relationship between mRNA stability and length: An old question with a new twist. Biochem. Genet. 45:131-137
- Hou W-R, Wang H-F, Niu D-K (2006) Replication-associated strand asymmetries in vertebrate genomes and implications for replicon size, DNA replication origin, and termination. Biochem. Biophys. Res. Commun. 344:1258-1262
- Niu D-K (2005) Low-level illegitimate transcription of genes may be to silence the genes. Biochem. Biophys. Res. Commun. 337:413-414
- Niu D-K, Hou W-R, Li S-W (2005) mRNA-mediated intron losses: evidence from extraordinarily large exons. Mol. Biol. Evol. 22:1475-1481
- Niu DK, Lin K, Zhang D-Y (2003) Strand compositional asymmetries of nuclear DNA in eukaryotes. J. Mol. Evol. 57:325-334
- Niu DK, Chen JK, Liu YD (2001) Margulis' theory on division of labour in cells revisited. Acta Biotheor. 49:23-28
- Niu DK, Chen JK (1998) Origin of cancerous cells from tumours. Acta Biotheor. 46:379-381
- Niu DK, Chen JK (1997) Evolutionary advantages of cell specialization: Save and protect DNA. J. Theor. Biol. 187:39-43
- Niu DK, Wang MG, Wang YF (1997) Plant cellular osmotica. Acta Biotheor. 45:161-169
- Niu DK, Wang YF (1995) Why animals have tumors. Acta Biotheor. 43:279-280
- And several papers in Chinese with English abstracts.
- for abstracts and links to fulltexts, please search Pubmed[1]
