User:David M. Truong

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Contact Info

David M. Truong (an artistic interpretation)

I work in the Laboratory of Alan M. Lambowitz at The University of Texas at Austin. I learned about OpenWetWare from surfing the net, and I've joined because I'm Wiki-editing a course, CH391L: Synthetic Biology..


  • 2007-Present, PhD Candidate, The University of Texas at Austin
  • 2001-2005, BS, University of California, San Diego

Research interests

  1. RNA world
  2. Genetic Engineering
  3. Gene Therapy
  4. Directed Evolution/Biomolecular Engineering


  1. Nagle MA, Truong DM, Dnyanmote AV, Ahn SY, Eraly SA, Wu W, and Nigam SK. Analysis of three-dimensional systems for developing and mature kidneys clarifies the role of OAT1 and OAT3 in antiviral handling. J Biol Chem. 2011 Jan 7;286(1):243-51. DOI:10.1074/jbc.M110.139949 | PubMed ID:20921221 | HubMed [Paper8]
  2. Wu W, Kitamura S, Truong DM, Rieg T, Vallon V, Sakurai H, Bush KT, Vera DR, Ross RS, and Nigam SK. Beta1-integrin is required for kidney collecting duct morphogenesis and maintenance of renal function. Am J Physiol Renal Physiol. 2009 Jul;297(1):F210-7. DOI:10.1152/ajprenal.90260.2008 | PubMed ID:19439520 | HubMed [Paper7]
  3. Vallon V, Eraly SA, Wikoff WR, Rieg T, Kaler G, Truong DM, Ahn SY, Mahapatra NR, Mahata SK, Gangoiti JA, Wu W, Barshop BA, Siuzdak G, and Nigam SK. Organic anion transporter 3 contributes to the regulation of blood pressure. J Am Soc Nephrol. 2008 Sep;19(9):1732-40. DOI:10.1681/ASN.2008020180 | PubMed ID:18508962 | HubMed [Paper6]
  4. Truong DM, Kaler G, Khandelwal A, Swaan PW, and Nigam SK. Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination. J Biol Chem. 2008 Mar 28;283(13):8654-63. DOI:10.1074/jbc.M708615200 | PubMed ID:18174163 | HubMed [Paper5]
  5. Kaler G, Truong DM, Khandelwal A, Nagle M, Eraly SA, Swaan PW, and Nigam SK. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem. 2007 Aug 17;282(33):23841-53. DOI:10.1074/jbc.M703467200 | PubMed ID:17553798 | HubMed [Paper4]
  6. Kaler G, Truong DM, Sweeney DE, Logan DW, Nagle M, Wu W, Eraly SA, and Nigam SK. Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions. Biochem Biophys Res Commun. 2006 Dec 29;351(4):872-6. DOI:10.1016/j.bbrc.2006.10.136 | PubMed ID:17094945 | HubMed [Paper3]
  7. Bhatnagar V, Xu G, Hamilton BA, Truong DM, Eraly SA, Wu W, and Nigam SK. Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3). J Hum Genet. 2006;51(6):575-580. DOI:10.1007/s10038-006-0398-1 | PubMed ID:16648942 | HubMed [Paper2]
  8. Eraly SA, Vallon V, Vaughn DA, Gangoiti JA, Richter K, Nagle M, Monte JC, Rieg T, Truong DM, Long JM, Barshop BA, Kaler G, and Nigam SK. Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. J Biol Chem. 2006 Feb 24;281(8):5072-83. DOI:10.1074/jbc.M508050200 | PubMed ID:16354673 | HubMed [Paper1]

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