User:David Breslow
I am a new member of OpenWetWare!
Contact Info
- David Breslow
- Stanford University
- Beckman Center, Rm B109
- 279 Campus Drive
- Stanford, CA 94305-5345
- Email me through OpenWetWare
I work in Max Nachury's lab at Stanford University.
Education
- 2010, PhD, University of California, San Francisco. Advisor: Prof. Jonathan S. Weissman
- 2004, A.B., Harvard University
Research interests
I'm investigating the role of primary cilia in signal transduction. In particular, I'm studying how the dynamic entry and exit of proteins from this organelle is coupled to its unique role in organizing signaling pathways.
Publications
• Roelants F.M.*, Breslow D.K.*, Muir A., Bodenmiller B., Weissman J.S., Thorner J.T. Control of sphingolipid homeostasis: Protein Kinase Ypk1 Regulates Orm1 and Orm2. Proc. Natl. Acad. Sci. USA, in press.
• Seo S., Zhang Q., Bugge K., Breslow D.K., Searby C.C., Nachury M.V., Sheffield V.C. A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened. PLoS Genetics. 7(11): e1002358. link
• Breslow D.K. and Nachury M.V., (2011). Primary Cilia: How to Keep the Riff-Raff in the Plasma Membrane. Current Biology. 21(11): R434-436. link
• Breslow D.K. and Weissman J.S., (2010). Membranes in Balance: Mechanisms of Sphingolipid Homeostasis. Molecular Cell. 40(2): 267-279. [review article]. link
• Breslow D.K., Collins S.R., Bodenmiller B., Aebersold R., Simons K., Shevchenko A., Ejsing C.S., Weissman J.S., (2010). Orm Family Proteins Mediate Sphingolipid Homeostasis. Nature. 463(7284): 1048-1053. link
• Breslow D.K.*, Cameron D.M.*, Collins S.R., Schuldiner M., Stewart-Ornstein J., Newman H.W., Braun S., Madhani H.D., Krogan N.J., Weissman J.S., (2008). A Comprehensive Strategy Enabling High-Resolution Functional Analysis of the Yeast Genome. Nature Methods. 5(8): 711-718. link
• Newman J.R., Ghaemmaghami S., Ihmels J., Breslow D.K., Noble M., DeRisi J.L., Weissman J.S. (2006). Single-cell Proteomic Analysis of S. cerevisiae Reveals the Architecture of Biological Noise. Nature, 441(7095): 840-846. link
