User:Davd A Hiller

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Contact Info

Davd A Hiller (an artistic interpretation)

Education

  • 2005, PhD, University of California at Santa Barbara
  • 2000, BS, California Institute of Technology

Research interests

  1. Enzymology
  2. Nucleic Acids
  3. Drug Design

Publications

  1. Hiller DA, Zhong M, Singh V, and Strobel SA. Transition states of uncatalyzed hydrolysis and aminolysis reactions of a ribosomal P-site substrate determined by kinetic isotope effects. Biochemistry. 2010 May 11;49(18):3868-78. DOI:10.1021/bi901458x | PubMed ID:20359191 | HubMed [Paper1]
  2. Hiller DA and Perona JJ. Positively charged C-terminal subdomains of EcoRV endonuclease: contributions to DNA binding, bending, and cleavage. Biochemistry. 2006 Sep 26;45(38):11453-63. DOI:10.1021/bi0606400 | PubMed ID:16981705 | HubMed [Paper2]
  3. Hiller DA, Rodriguez AM, and Perona JJ. Non-cognate enzyme-DNA complex: structural and kinetic analysis of EcoRV endonuclease bound to the EcoRI recognition site GAATTC. J Mol Biol. 2005 Nov 18;354(1):121-36. DOI:10.1016/j.jmb.2005.09.046 | PubMed ID:16236314 | HubMed [Paper3]
  4. Hiller DA, Fogg JM, Martin AM, Beechem JM, Reich NO, and Perona JJ. Simultaneous DNA binding and bending by EcoRV endonuclease observed by real-time fluorescence. Biochemistry. 2003 Dec 16;42(49):14375-85. DOI:10.1021/bi035520w | PubMed ID:14661948 | HubMed [Paper4]

All Medline abstracts: PubMed | HubMed