User:Cameron Mura

Contact Info

Cameron Mura (an artistic interpretation)

• Cameron Mura
  University of Virginia
  Department of Chemistry
  McCormick Road, Box 400319
  Charlottesville, VA 22904-4319 USA
  

• Email me through OpenWetWare

Educational Background & Professional Experience

In reverse chronological order:

• Assistant Professor, Department of Chemistry, Univ of Virginia (Sep-2008 → present)
• Research Assistant Professor, Department of Chemistry, Univ of Virginia (Jan-2008 → Aug-2008)
• Sloan/DOE Postdoctoral Fellow in Computational Molecular Biology, Univ of California, San Diego (Oct-2002 → Dec- 2007; with Andy McCammon)
• Postdoctoral Research Associate in Structural Biology, UCLA (May-2002 → Oct-2002; with David Eisenberg)
• PhD in Biochemistry & Molecular Biology, UCLA (Sep 1996 → May 2002; with David Eisenberg)
• BS in Chemistry, with Highest Honors, Georgia Institute of Technology (Sep 1992 → Mar-1996; with Loren Williams)

Current Activities

• I work in the Mura Lab at the University of Virginia. I learned about OpenWetWare from online web searches (Google) and colleagues. I've joined because I would like to learn about OWW, add my group's website, and would also like to contribute in the areas of my training/expertise (crystallography, structural and computational biology, RNA-binding proteins).

Research Interests

• Structural biology and molecular biophysics of protein/nucleic acid assemblies, particularing those involved in RNA processing
• Macromolecular crystallography
• Molecular dynamics simulations and related computational methods
• Bioinformatics, particularly as related to protein family evolution / gene duplication / symmetric assemblies

Publications

1. Presnell SR, Patil GS, Mura C, Jude KM, Conley JM, Bertrand JA, Kam CM, Powers JC, and Williams LD. Oxyanion-mediated inhibition of serine proteases. Biochemistry. 1998 Dec 1;37(48):17068-81. DOI:10.1021/bi981636u |
2. Mura C, Cascio D, Sawaya MR, and Eisenberg DS. The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core. Proc Natl Acad Sci U S A. 2001 May 8;98(10):5532-7. DOI:10.1073/pnas.091102298 |
3. Wang S, Mura C, Sawaya MR, Cascio D, and Eisenberg D. Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets. Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):571-8. DOI:10.1107/s0907444902001191 |
4. Mura C, Katz JE, Clarke SG, and Eisenberg D. Structure and function of an archaeal homolog of survival protein E (SurEalpha): an acid phosphatase with purine nucleotide specificity. J Mol Biol. 2003 Mar 7;326(5):1559-75. DOI:10.1016/s0022-2836(03)00056-1 |
5. Mura C, Kozhukhovsky A, Gingery M, Phillips M, and Eisenberg D. The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs). Protein Sci. 2003 Apr;12(4):832-47. DOI:10.1110/ps.0224703 |
6. Mura C, Phillips M, Kozhukhovsky A, and Eisenberg D. Structure and assembly of an augmented Sm-like archaeal protein 14-mer. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4539-44. DOI:10.1073/pnas.0538042100 |
7. Arluison V, Mura C, Guzmán MR, Liquier J, Pellegrini O, Gingery M, Régnier P, and Marco S. Three-dimensional structures of fibrillar Sm proteins: Hfq and other Sm-like proteins. J Mol Biol. 2006 Feb 10;356(1):86-96. DOI:10.1016/j.jmb.2005.11.010 |
8. Arluison V, Mutyam SK, Mura C, Marco S, and Sukhodolets MV. Sm-like protein Hfq: location of the ATP-binding site and the effect of ATP on Hfq-- RNA complexes. Protein Sci. 2007 Sep;16(9):1830-41. DOI:10.1110/ps.072883707 |

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9. ISBN:0879697164

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