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- Benjamin Bolduc
- Riffe Building 932
- Ohio State University
- Columbus, OH, USA
- 2014, PhD, Montana State University, Bozeman, MT
- 2007, BS, Stonehill College, Easton, MA
Background and Research interests
Ben joined the Sullivan and Rich lab in May 2015 from Montana State University, Bozeman. His Ph.D. work, under the guidance of Mark Young, focused on isolating RNA viruses from acidic, thermophilic environments in Yellowstone National Park and developing bioinformatic/wet lab protocols to generate and analyze viral metagenomes out of these extreme environments. He continued his PhD work into his postdoc at MSU and also began work developing network-based tools to analyze viral metagenomes and using large scale databases for storing sequence information.
In the Sullivan lab, Ben has worked on continued development of the phageFISH technique to probe the influence of nutrients on virus-host interactions. He is also continuing the development of vContact - a tool employing gene similarity networks to identify known and unknown viral sequences from a variety of microbial and viral datasets. In the Rich lab, Ben is responsible for the development of the IsoGenie database - responsible for the storing and integration of a wide variety of data types from more than a dozen labs. This database can be leveraged for network analytics, allowing integrated projects to uncovert he nature of viruses in natural ecosystems and ultimately their intimate relation with their hosts.
Bolduc, B, Youens-Clark, K., Roux, S., Hurwitz B.L., Sullivan, M.B. (2016) iVirus: facilitating new insights in viral ecology with software and community data sets imbedded in a cyberinfrastructure. ISME J. In press.
Bolduc, B., J. Wirth, A. Mazurie, and M.J. Young. (2015) Viral Community Composition in Yellowstone Acidic Hot Springs Assessed by Network Analysis. ISME J. 9:2162-2177.
Dellas, N., J.C. Snyder, B. Bolduc, and M.J. Young. (2014) Archaeal viruses: diversity, replication and structure. (invited review) Annu. Rev. Virol. 1: 399-426.
Bolduc, B., D.P. Shaughnessy, Y. I. Wolf, E.V. Koonin, F.F. Roberto, and M.J. Young. (2012) Identification of Novel Positive-Strand RNA Viruses by Metagenomic Analysis of Archaea-Dominated Yellowstone Hot Springs. J. Virology. 86:10.
Snyder, J.C., B. Bolduc, M.M. Bateson, and M.J. Young (2011) The prevalence of STIV c92-like proteins within acidic thermal environments. Adv. Virol. 2011:1.
Brammer, L.A., B. Bolduc, J.L. Kass, K.M. Felice, C.J. Noren, and M.F. Hall (2007) A target-unrelated peptide in an M13 phage display library traced to an advantageous mutation in the gene II ribosome-binding site. Anal. Biochem. 373:1