User:Bajpai Astha

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Contact Info

Bajpai Astha (an artistic interpretation)

I work in the Your Lab at XYZ University. I learned about OpenWetWare from iGEM, and I've joined because protein targeting to cell membranes; molecular mechanisms. Molecular chaperone action in posttranslational protein targeting.

ASTHA BAJPAIRESEARCH ASSOCIATE BIOMEDICAL RESERACH CENTER, SHEFFIELD HALLAM UNIVERSITY SHEFFIELD,ENGLAND,UK

IMPORT OF AVSUNVIROIDAE AND VIROID TRAFICKING

Example.jpg The multi‑domain FKBP TWISTED DWARF1 (TWD1)/FKBP42, has been shown to reside on both the vacuolar and plasma membranes it interacts in mirror image with two pairs of ABC transporters, MRP1/ MRP2 and PGP1/PGP19(MDR1), respectively.

Twisted dwarf1 and pgp1/pgp19 mutants display strongly overlapping phenotypes, including reduction and disorientation of growth, suggesting functional interaction All FKBP‑type immunophilins share a characteristic peptidyl‑prolyl cis‑trans isomerase domain Twenty-three FKBP‑type proteins have been identified in the Arabidopsis thaliana genome, however, the function of individual FKBPs in plant biology is poorly understood Example.jpg

Research interests

RNA-templated RNA replication Chrysanthemum chlorotic mottle viroid Ascochyta (Mycosphaerella)

Publications

  1. Goldbeter A and Koshland DE Jr. An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A. 1981 Nov;78(11):6840-4. PubMed ID:6947258 | HubMed [Paper1]
  2. JACOB F and MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318-56. PubMed ID:13718526 | HubMed [Paper2]
    leave a comment about a paper here
  3. Mark Ptashne. A genetic switch. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press, 2004. ISBN:0879697164 [Book1]
All Medline abstracts: PubMed | HubMed

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