User:Arnold Pizzey

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Contact Info

Arnold Pizzey (an artistic interpretation)

• Arnold Pizzey
• University College London Department Of Research Haematology
• Address 1
• Address 2
• City, State, Country etc.
• Email me through OpenWetWare

I work in the department of Haematology at University College London. I learned about OpenWetWare from Gooke, and I've joined because I have been working as a practical scientist at UCL for 30 years and would like to pass on my knowledge to others.

Education

• Year, PhD, Institute
• Year, MS, Institute
• Year, BS, Institute

Research interests

1. Interest 1
2. Interest 2
3. Interest 3

Publications

1. Lawrie AS, Pizzey A, Trompeter S, Meiselman H, Mohandas N, Dumanski JP, and Westerman MP. Procoagulant activity in patients with sickle cell trait. Blood Coagul Fibrinolysis. 2012 Jun;23(4):268-70. DOI:10.1097/MBC.0b013e32835187f8 |
2. Calleja-Agius J, Jauniaux E, Pizzey AR, and Muttukrishna S. Investigation of systemic inflammatory response in first trimester pregnancy failure. Hum Reprod. 2012 Feb;27(2):349-57. DOI:10.1093/humrep/der402 |
3. Calleja-Agius J, Muttukrishna S, Pizzey AR, and Jauniaux E. Pro- and antiinflammatory cytokines in threatened miscarriages. Am J Obstet Gynecol. 2011 Jul;205(1):83.e8-16. DOI:10.1016/j.ajog.2011.02.051 |
4. Speyer BE, Pizzey AR, Ranieri M, Joshi R, Delhanty JD, and Serhal P. Fall in implantation rates following ICSI with sperm with high DNA fragmentation. Hum Reprod. 2010 Jul;25(7):1609-18. DOI:10.1093/humrep/deq116 |
5. Peggs KS, Verfuerth S, Pizzey A, Chow SL, Thomson K, and Mackinnon S. Cytomegalovirus-specific T cell immunotherapy promotes restoration of durable functional antiviral immunity following allogeneic stem cell transplantation. Clin Infect Dis. 2009 Dec 15;49(12):1851-60. DOI:10.1086/648422 |
6. Abidova SS, Khoroshaev VA, and Leonov FV. [Morphofunctional characteristics of the heart mitochondria during adrenergic stimulation and blockade under ketamine anesthesia]. Anesteziol Reanimatol. 1990 Nov-Dec(6):12-5.
7. Kolman P, Pica A, Carvou N, Boyde A, Cockcroft S, Loesch A, Pizzey A, Simeoni M, Capasso G, and Unwin RJ. Insulin uptake across the luminal membrane of the rat proximal tubule in vivo and in vitro. Am J Physiol Renal Physiol. 2009 May;296(5):F1227-37. DOI:10.1152/ajprenal.90351.2008 |
8. Smith BN, Ancliff PJ, Pizzey A, Khwaja A, Linch DC, and Gale RE. Homozygous HAX1 mutations in severe congenital neutropenia patients with sporadic disease: a novel mutation in two unrelated British kindreds. Br J Haematol. 2009 Mar;144(5):762-70. DOI:10.1111/j.1365-2141.2008.07493.x |
9. Kyriakou C, Rabin N, Pizzey A, Nathwani A, and Yong K. Factors that influence short-term homing of human bone marrow-derived mesenchymal stem cells in a xenogeneic animal model. Haematologica. 2008 Oct;93(10):1457-65. DOI:10.3324/haematol.12553 |
10. Westerman M, Pizzey A, Hirschman J, Cerino M, Weil-Weiner Y, Ramotar P, Eze A, Lawrie A, Purdy G, Mackie I, and Porter J. Microvesicles in haemoglobinopathies offer insights into mechanisms of hypercoagulability, haemolysis and the effects of therapy. Br J Haematol. 2008 Jul;142(1):126-35. DOI:10.1111/j.1365-2141.2008.07155.x |
11. Appasamy M, Muttukrishna S, Pizzey AR, Ozturk O, Groome NP, Serhal P, and Jauniaux E. Relationship between male reproductive hormones, sperm DNA damage and markers of oxidative stress in infertility. Reprod Biomed Online. 2007 Feb;14(2):159-65. DOI:10.1016/s1472-6483(10)60783-3 |
12. Kyriakou CA, Yong KL, Benjamin R, Pizzey A, Dogan A, Singh N, Davidoff AM, and Nathwani AC. Human mesenchymal stem cells (hMSCs) expressing truncated soluble vascular endothelial growth factor receptor (tsFlk-1) following lentiviral-mediated gene transfer inhibit growth of Burkitt's lymphoma in a murine model. J Gene Med. 2006 Mar;8(3):253-64. DOI:10.1002/jgm.840 |
13. Gale RE, Hills R, Pizzey AR, Kottaridis PD, Swirsky D, Gilkes AF, Nugent E, Mills KI, Wheatley K, Solomon E, Burnett AK, Linch DC, Grimwade D, and NCRI Adult Leukaemia Working Party. Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia. Blood. 2005 Dec 1;106(12):3768-76. DOI:10.1182/blood-2005-04-1746 |
14. Starke R, Harrison P, Mackie I, Wang G, Erusalimsky JD, Gale R, Massé JM, Cramer E, Pizzey A, Biggerstaff J, and Machin S. The expression of prion protein (PrP(C)) in the megakaryocyte lineage. J Thromb Haemost. 2005 Jun;3(6):1266-73. DOI:10.1111/j.1538-7836.2005.01343.x |
15. Rew SB, Peggs K, Sanjuan I, Pizzey AR, Koishihara Y, Kawai S, Kosaka M, Ozaki S, Chain B, and Yong KL. Generation of potent antitumor CTL from patients with multiple myeloma directed against HM1.24. Clin Cancer Res. 2005 May 1;11(9):3377-84. DOI:10.1158/1078-0432.CCR-04-0650 |
16. Fricke B, Jarvis HG, Reid CD, Aguilar-Martinez P, Robert A, Quittet P, Chetty M, Pizzey A, Cynober T, Lande WF, Mentzer WC, Düring M, Winter S, Delaunay J, and Stewart GW. Four new cases of stomatin-deficient hereditary stomatocytosis syndrome: association of the stomatin-deficient cryohydrocytosis variant with neurological dysfunction. Br J Haematol. 2004 Jun;125(6):796-803. DOI:10.1111/j.1365-2141.2004.04965.x |
17. Ahmed F, Ings SJ, Pizzey AR, Blundell MP, Thrasher AJ, Ye HT, Fahey A, Linch DC, and Yong KL. Impaired bone marrow homing of cytokine-activated CD34+ cells in the NOD/SCID model. Blood. 2004 Mar 15;103(6):2079-87. DOI:10.1182/blood-2003-06-1770 |
18. Peggs KS, Verfuerth S, Pizzey A, Khan N, Guiver M, Moss PA, and Mackinnon S. Adoptive cellular therapy for early cytomegalovirus infection after allogeneic stem-cell transplantation with virus-specific T-cell lines. Lancet. 2003 Oct 25;362(9393):1375-7. DOI:10.1016/S0140-6736(03)14634-X |
19. D'Sa S, Peggs K, Pizzey A, Verfuerth S, Thuraisundaram D, Watts M, White H, Hale G, Waldmann H, Goldstone A, Mackinnon S, and Yong K. T- and B-cell immune reconstitution and clinical outcome in patients with multiple myeloma receiving T-cell-depleted, reduced-intensity allogeneic stem cell transplantation with an alemtuzumab-containing conditioning regimen followed by escalated donor lymphocyte infusions. Br J Haematol. 2003 Oct;123(2):309-22. DOI:10.1046/j.1365-2141.2003.04612.x |
20. Fricke B, Argent AC, Chetty MC, Pizzey AR, Turner EJ, Ho MM, Iolascon A, von Düring M, and Stewart GW. The "stomatin" gene and protein in overhydrated hereditary stomatocytosis. Blood. 2003 Sep 15;102(6):2268-77. DOI:10.1182/blood-2002-06-1705 |
21. Peggs KS, Verfuerth S, Pizzey A, Khan N, Moss P, Goldstone AH, Yong K, and Mackinnon S. Reconstitution of T-cell repertoire after autologous stem cell transplantation: influence of CD34 selection and cytomegalovirus infection. Biol Blood Marrow Transplant. 2003 Mar;9(3):198-205. DOI:10.1053/bbmt.2003.50010 |
22. Ardeshna KM, Pizzey AR, Walker SJ, Devereux S, and Khwaja A. The upregulation of CC chemokine receptor 7 and the increased migration of maturing dendritic cells to macrophage inflammatory protein 3beta and secondary lymphoid chemokine is mediated by the p38 stress-activated protein kinase pathway. Br J Haematol. 2002 Dec;119(3):826-9. DOI:10.1046/j.1365-2141.2002.03869.x |
23. Yong KL, Fahey A, Pizzey A, and Linch DC. Influence of cell cycling and cell division on transendothelial migration of CD34+ cells. Br J Haematol. 2002 Nov;119(2):500-9. DOI:10.1046/j.1365-2141.2002.03837.x |
24. Forbes LV, Gale RE, Pizzey A, Pouwels K, Nathwani A, and Linch DC. An activating mutation in the transmembrane domain of the granulocyte colony-stimulating factor receptor in patients with acute myeloid leukemia. Oncogene. 2002 Sep 5;21(39):5981-9. DOI:10.1038/sj.onc.1205767 |
25. Grimwade D, Outram SV, Flora R, Ings SJ, Pizzey AR, Morilla R, Craddock CF, Linch DC, and Solomon E. The T-lineage-affiliated CD2 gene lies within an open chromatin environment in acute promyelocytic leukemia cells. Cancer Res. 2002 Aug 15;62(16):4730-5.
26. Perera D, Pizzey A, Campbell A, Katz M, Porter J, Petrou M, Irvine DS, and Chatterjee R. Sperm DNA damage in potentially fertile homozygous beta-thalassaemia patients with iron overload. Hum Reprod. 2002 Jul;17(7):1820-5. DOI:10.1093/humrep/17.7.1820 |
27. Yong KL, Fahey A, Pahal G, Linch DC, Pizzey A, Thomas NS, Jauniaux E, Kinnon C, and Thrasher AJ. Fetal haemopoietic cells display enhanced migration across endothelium. Br J Haematol. 2002 Feb;116(2):392-400. DOI:10.1046/j.1365-2141.2002.03273.x |
28. Peggs K, Verfuerth S, Pizzey A, Ainsworth J, Moss P, and Mackinnon S. Characterization of human cytomegalovirus peptide-specific CD8(+) T-cell repertoire diversity following in vitro restimulation by antigen-pulsed dendritic cells. Blood. 2002 Jan 1;99(1):213-23. DOI:10.1182/blood.v99.1.213 |
29. Ardeshna KM, Pizzey AR, Devereux S, and Khwaja A. The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells. Blood. 2000 Aug 1;96(3):1039-46.
30. Ardeshna KM, Pizzey AR, Thomas NS, Orr S, Linch DC, and Devereux S. Monocyte-derived dendritic cells do not proliferate and are not susceptible to retroviral transduction. Br J Haematol. 2000 Mar;108(4):817-24. DOI:10.1046/j.1365-2141.2000.01956.x |
31. Rioja A, Pizzey AR, Marson CM, and Thomas NS. Preferential induction of apoptosis of leukaemic cells by farnesol. FEBS Lett. 2000 Feb 11;467(2-3):291-5. DOI:10.1016/s0014-5793(00)01168-6 |
32. Yong K, Fahey A, Reeve L, Nicholls C, Thomas NS, Pizzey A, Ings SJ, Watts MJ, and Linch DC. Cord blood progenitor cells have greater transendothelial migratory activity and increased responses to SDF-1 and MIP-3beta compared with mobilized adult progenitor cells. Br J Haematol. 1999 Nov;107(2):441-9. DOI:10.1046/j.1365-2141.1999.01714.x |
33. Lam EW, Glassford J, van der Sman J, Banerji L, Pizzey AR, Shaun N, Thomas B, and Klaus GG. Modulation of E2F activity in primary mouse B cells following stimulation via surface IgM and CD40 receptors. Eur J Immunol. 1999 Oct;29(10):3380-9. DOI:10.1002/(SICI)1521-4141(199910)29:10<3380::AID-IMMU3380>3.0.CO;2-C |
34. Coffin RS, Thomas SK, Thomas NS, Lilley CE, Pizzey AR, Griffiths CH, Gibb BJ, Wagstaff MJ, Inges SJ, Binks MH, Chain BM, Thrasher AJ, Rutault K, and Latchman DS. Pure populations of transduced primary human cells can be produced using GFP expressing herpes virus vectors and flow cytometry. Gene Ther. 1998 May;5(5):718-22. DOI:10.1038/sj.gt.3300634 |
35. Thomas NS, Pizzey AR, Tiwari S, Williams CD, and Yang J. p130, p107, and pRb are differentially regulated in proliferating cells and during cell cycle arrest by alpha-interferon. J Biol Chem. 1998 Sep 11;273(37):23659-67. DOI:10.1074/jbc.273.37.23659 |
36. Golay J, Broccoli V, Lamorte G, Bifulco C, Parravicini C, Pizzey A, Thomas NS, Delia D, Ferrauti P, Vitolo D, and Introna M. The A-Myb transcription factor is a marker of centroblasts in vivo. J Immunol. 1998 Mar 15;160(6):2786-93.
37. Gomperts BD, Hide I, Bennett JP, Pizzey A, and Tatham PE. The exocytotic reaction of permeabilized rat mast cells. An all-or-none response. Ann N Y Acad Sci. 1994 Mar 9;710:217-31. DOI:10.1111/j.1749-6632.1994.tb26630.x |
38. Hide I, Bennett JP, Pizzey A, Boonen G, Bar-Sagi D, Gomperts BD, and Tatham PE. Degranulation of individual mast cells in response to Ca2+ and guanine nucleotides: an all-or-none event. J Cell Biol. 1993 Nov;123(3):585-93. DOI:10.1083/jcb.123.3.585 |
39. Roberts PJ, Pizzey AR, Khwaja A, Carver JE, Mire-Sluis AR, and Linch DC. The effects of interleukin-8 on neutrophil fMetLeuPhe receptors, CD11b expression and metabolic activity, in comparison and combination with other cytokines. Br J Haematol. 1993 Aug;84(4):586-94. DOI:10.1111/j.1365-2141.1993.tb03132.x |
40. Howard MK, Burke LC, Mailhos C, Pizzey A, Gilbert CS, Lawson WD, Collins MK, Thomas NS, and Latchman DS. Cell cycle arrest of proliferating neuronal cells by serum deprivation can result in either apoptosis or differentiation. J Neurochem. 1993 May;60(5):1783-91. DOI:10.1111/j.1471-4159.1993.tb13404.x |
41. Roberts PJ, Pizzey AR, and Linch DC. The effect of inhibition of leukotriene synthesis on the activity of interleukin-8 and granulocyte-macrophage colony-stimulating factor. Mediators Inflamm. 1993;2(3):211-6. DOI:10.1155/S0962935193000286 |
42. Roberts PJ, Yong KL, Khwaja A, Johnson BV, Pizzey AR, Carver JE, Addison IE, and Linch DC. Pentoxifylline at clinically achievable levels inhibits FMLP-induced neutrophil responses, but not priming, upregulation of cell-adhesion molecules, or migration induced by GM-CSF. Eur J Haematol. 1993 Jan;50(1):1-10. DOI:10.1111/j.1600-0609.1993.tb00066.x |
43. Roberts PJ, Devalia V, Faint R, Pizzey A, Bainton AL, Thomas NS, Pilkington GR, and Linch DC. Differentiation-linked activation of the respiratory burst in a monocytic cell line (U937) via Fc gamma RII. A study of activation pathways and their regulation. J Immunol. 1991 Nov 1;147(9):3104-15.

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