User:Ana-Teresa Maia

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Contact Info

Ana-Teresa Maia (an artistic interpretation)
  • Ana-Teresa Maia

Group Leader of Cancer Functional Genomics Group
Carrer Integration Grant Holder - Marie Curie
Assistant Professor

IBB/CBME Laboratório Associado
Department of Biomedical Sciences and Medicine
University of Algarve
Gambelas, Faro, Portugal
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Education

  • 2003, PhD, Institute of Cancer Research, London, U.K.
  • 1999, MS, Imperial College of Science, Technology and Medicine, London, U.K.
  • 1997, BS, Faculty of Science and Technology, New University of Lisbon, Monte da Caparica, Portugal

Research Interests

2012 - present : Assistant Professor, University of Algarve Program in Regenerative Medicine, Department of Biomedical Sciences and Medicine Maternity Leave: March 2013- September 2013

2012 - present : Group Leader, Associate Laboratory IBB/CBME Cancer Functional Genomics Group

10/2008 – 12/2011 : Senior Research Associate, University of Cambridge Department of Oncology at Cambridge Research Institute-CRUK Supervisor: Professor Sir Bruce Ponder

10/2006 - 9/2008 : Research Associate, University of Cambridge Department of Oncology at Cambridge Research Institute-CRUK Supervisor: Professor Sir Bruce Ponder

9/2003 - 9/2006 : Research Associate, University of Cambridge Department of Oncology at Hutchison/MRC Institute Supervisors: Professors Sir Bruce Ponder and Carlos Caldas

2/2001 : Visiting Student to Professor Andrea Biondi's group Clinica Pediatrica dell’Università degli Studi di Milano-Bicocca, Ospedale San Gerardo di Monza

9/1999 - 8/2003 : PhD Student, Institute of Cancer Research Leukaemia Research Fund Centre Supervisor: Professor Mel Greaves

9/1998 - 8/1999 : MSc Student, Imperial College of Science, Technology and Medicine Supervisor: Professor Mel Greaves

9/1996 - 8/1998 : Researcher in training, New University of Lisbon Department of Genetics, Faculty of Medical Sciences


Research Interests

I am interested in studying allelic imbalance in gene expression, a common feature of our genome. Due to regulatory polymorphisms, which can occur both in cis- and in trans-, a large number of our genes are preferentially expressed from one allele. This unequal expression can contribute to susceptibility to common diseases. My main aim is to try to use this concept to develop a new method to study predisposition to breast cancer. Additionally, I am investigating the role that this imbalance can play in tumour biology, namely in the effect of mutations and treatment response.

Publications

For all publications http://publicationslist.org/ana-teresa.maia

Selected Papers

  1. Curtis CN et al. (2012) Nature:486(7403):346-52 pmid= 22522925 [Paper1]
  2. Maia AT et al. (2012) Breast Cancer Research:R63pmid= 22513257 [Paper2]
  3. Maia AT et al. (2009) Breast Cancer Research:R88 pmid= 20003265 [Paper3]
  4. Meyer KM, Maia AT et al. (2008) PLoS Biology:6(5):e108 pmid= 18462018 [Paper4]
  5. Udler M, Maia AT et al. (2007) Journal of Clinical Oncology:25(21):3015-23 pmid= 17634480 [Paper5]

Funding

  • 2013 - 2015 “Cis-regulation of somatic mutations in breast and ovarian cancers”; PTDC/BIM-ONC/1338/2012; Foundation for Science and Technology, Portugal
  • 2012 - 2016 Marie Curie Integration Grant, GenCar - Genetic Control of Gene Expression in Cancer Risk, FP7-MC-CIG, European Union
  • 2009 – 2010 Breast Cancer Research Foundation Grant, U.S.A., Differential Allelic Expression Analysis of Susceptibility Loci in Breast Cancer, USA
  • 2008 – 2009 Breast Cancer Research Foundation Grant, U.S.A., Differential Allelic Expression Analysis of Susceptibility Loci in Breast Cancer, USA

Teaching

Integrated Masters in Medicine

         * PBL classes to 1st and 2nd years
         * Seminars in Basic Sciences
         * Coordinator of Student Chosen Module for 2 year (5 weeks training in laboratory or clinical work))

Masters of Science in Oncobiology - Molecular Mechanisms of Cancer

         Vice-Director
         * Oncogenetics and Oncogenomics
         * Genetic Toxicology
         * Clinical Oncology

Masters of Science in BIomedical Sciences

         * Computational Biology

Undergraduate Degree in BIomedical Sciences

         * Human Genetics


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