Photolytic crosslinking to probe protein-protein and protein-matrix interactions in lyophilized powders. LK Iyer, BS Moorthy, and EM Topp,, submitted to Molecular Pharmaceutics, March 5, 2015.
Cocrystalline solids of telaprevir with enhanced oral absorption. K Stavropoulos, S Johnston, Y Zhang, G Bhisetti, M Hurrey, P Hurter, E Topp, and I Kadiyala, Journal of Pharmaceutical Sciences, submitted January 14, 2015. 113.
[Analyzing subvisible particles in protein drug products: A comparison of dynamic light scattering (DLS) and resonant mass measurement (RMM). J Panchal, J Kotarek, E Marszal,and EM Topp. AAPS Journal, 16/3: 440-451, 2014. DOI: 10.1208/s12248-014-9579-6.
Effect of deamidation on the in vivo fate of monoclonal antibodies. S Chandrasekhar, BS Moorthy, B Xie and EM Topp, in Biobetters: Protein Engineering to Approach the Curative, A Rosenberg and B Demeule (eds.), Advances in Pharmaceutical Sciences series, Academic Press, New York, invited.
Approaches to pharmaceutical product design. BC Roughton, KV Camarada and EM Topp, in Ullman’s Encyclopedia of Industrial Chemistry, Wiley-VCH Verlag GmbH & Co., Mannheim, Germany, 2012. DOI: 10.1002/14356007.o22_o08; published online 15 JAN 2013.
Probing protein conformation in lyophilized powders by hydrogen/deuterium exchange: Deuterium uptake kinetics in lyophilized myoglobin powders. A Sophocleous and EM Topp. Molecular Pharmaceutics. Invited manuscript for special issue, “Advances in Biophysical and Bioanalytical Protein Characterization”. Submitted August 17, 2011. Reviewers’ comments received November 16, 2011.
Localized effects of hydration on lyophilized myoglobin by hydrogen/deuterium exchange mass spectrometry. A.M. Sophocleous, J Zhang and EM Topp, submitted to Biophysical Journal, June 24, 2011. Reviewers’ comments received August 15, 2011. Revised version submitted October 29, 2011.
Proteins and peptides: Physical and chemical stability. A Sophocleous, J Zhang, L Iyer, S Chandrasekhar and EM Topp, Encyclopedia of Pharmaceutical Science and Technology, 4th ed., James Swarbrick, D.Sc., Ph.D., Editor. Informa Healthcare, New York, NY. Submitted April 26, 2011.