Talk:Harvard:Biophysics 101/2007/02/13/install-clustalw

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Mac OS X

  • Download source
  • Open a terminal window and do the following
    • cd to Desktop
    • extract the file (add z switch to tar if Safari didn't automatically gunzip)
    • enter the directory
    • compile clustalw
    • try running clustalw to make sure you comiled it successfully
    • copy clustalw to a place where python can find it (e.g. /usr/bin)
  • Example terminal commands
cd Desktop/
tar -xvf clustalw1.83.UNIX.tar.gz
cd clustalw1.83/
sudo sudo cp clustalw /usr/bin/


  • Download clustalw executable for Windows.
  • From the desktop, right click My Computer and click properties.
  • In the System Properties window, click on the Advanced tab.
  • In the Advanced section, click the Environment Variables button.
  • Finally, in the Environment Variables window, highlight the path variable in the Systems Variable section and click edit.
  • Add or modify the path lines with the paths you wish the computer to access. Each different directory is separated with a semicolon.
C:\Program Files;C:\Winnt;C:\Winnt\System32
  • Add the directory containing clustalw to your path.
  • Your final environmental variable would look like the following if you had extracted clustalw to C:\Documents and Settings\Mike\Desktop\clustalw (your desktop).
C:\Program Files;C:\Winnt;C:\Winnt\System32; C:\Documents and Settings\Mike\Desktop\clustalw