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Selected Publications

Courbet, A., Endy, D., Renard, E., Molina, F. & Bonnet, J.
Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates.
Science Transl. Med. 7, 289ra83–289ra83 (2015).

Courbet, A., Molina, F. & Amar, P.
Computing with Synthetic Protocells.
Acta Biotheor. (2015). doi:10.1007/s10441-015 9258-8

Thierry AR, Mouliere F, El Messaoudi S, Mollevi C, Lopez-Crapez E, Rolet F, Gillet B, Gongora C, Dechelotte P, Robert B, Del Rio M, Lamy PJ, Bibeau F, Nouaille M, Loriot V, Jarrousse AS, Molina F, Mathonnet M, Pezet D, Ychou M.
Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA.
Nat Med. 2014 Apr;20(4):430-5. doi: 10.1038/nm.3511. Epub 2014 Mar 23.

Schneider FS, Nguyen DL, Castro KL, Cobo S, Machado de Avila RA, Ferreira Nde A, Sanchez EF, Nguyen C, Granier C, Galéa P, Chávez-Olortegui C, Molina F.
Use of a synthetic biosensor for neutralizing activity-biased selection of monoclonal antibodies against atroxlysin-I, an hemorrhagic metalloproteinase from Bothrops atrox snake venom.
PLoS Negl Trop Dis. 2014 Apr 24;8(4):e2826. doi: 10.1371/journal.pntd.0002826. eCollection 2014 Apr.

Pérès S, Felicori L, Molina F.
Elementary flux modes analysis of functional domain networks allows a better metabolic pathway interpretation.
PLoS One. 2013 Oct 29;8(10):e76143. doi: 10.1371/journal.pone.0076143. eCollection 2013.

Norris V, Molina F, Gewirtz AT.
Hypothesis: bacteria control host appetites.
J Bacteriol. 2013 Feb;195(3):411-6. doi: 10.1128/JB.01384-12. Epub 2012 Nov 9. Review.

V. Norris, AR. Thierry, P. Amar, BI Holland, F. Molina,
The Mimic Chain Reaction
Journal of Molecular Microbiology and Biotechnology 22, 5 (2012) 335-343

Joerg Martin Buescher, Wolfram Liebermeister, Matthieu Jules, Markus Uhr, Jan Muntel, Eric Botella, Bernd Hessling, Roelco Jacobus Kleijn, Ludovic Le Chat, François Lecointe,Ulrike Mäder, Pierre Nicolas, Sjouke Piersma, Frank Rügheimer, Dörte Becher, Philippe Bessieres, Elena Bidnenko, Emma L. Denham, Etienne Dervyn, Kevin M. Devine, Geoff Doherty, Samuel Drulhe, Liza Felicori, Mark J. Fogg, Anne Goelzer, Annette Hansen,Colin R. Harwood, Michael Hecker, Sebastian Hubner, Claus Hultschig, Hanne Jarmer, Edda Klipp, Aurélie Leduc, Peter Lewis, Frank Molina, Philippe Noirot, Sabine Peres, Nathalie Pigeonneau, Susanne Pohl, Simon Rasmussen, Bernd Rinn, Marc Schaffer, Julian Schnidder, Benno Schwikowski, Jan Maarten Van Dijl, Patrick Veiga, Sean Walsh, Anthony J. Wilkinson, Jörg Stelling, Stéphane Aymerich, Uwe Sauer,
Global Network Reorganization During Dynamic Adaptations of Bacillus subtilis Metabolism
Science 335, 1099 (2012); DOI: 10.1126/science.1206871

V Norris, A Zemirline, P Amar, P Ballet, E Ben Jacob, G Bernot, G Beslon, E Fanchon, JL Giavitto, N Glade, P Greussay, Y Grondin, J Foster, G Hutzler, F Kepes, O Michel, G Misevic, F Molina, J Signorini, P Stano, AR Thierry, (2011)
Computing with bacterial constituents, cells and populations: from bioputing to bactoputing.
Theory Biosci. 2011 Mar 8. PMID:21384168

S. Rialle L Felicori, C. Lopes , S. Peres, P. Amar, A. Thierry and F. Molina,
BionetCAD an integrative approach to design and simulated synthetic biological networks
Bioinformatics. 2010 Sep 15;26(18):2298-304, PMID: 20628073. (IP 6.2)

S Peres, S Rialle, L Felicori, F Molina,
Formal language for detailed structure function annotation based on elementary bricks of action
Bioinformatics 2010 Jun 15;26(12):1542-7 (IP 6.2)

F Molina, M Dehmer, P Perco, A Graber, M Girolami, G Spasovski5, J P. Schanstra, A Vlahou,
Systems biology: opening new avenues in clinical research

A Thierry, V Norris, F Molina, M Schmutz,
Lipoplex nanostructures reveals a general self-organization of nucleic acids
Biochim Biophys Acta. 2009 May;1790(5):385-94.