Sriram Lab:Courses

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Core engineering courses taught by Dr. Sriram

ENCH215: Chemical Engineering Analysis (Fall 2008, Fall 2009, Fall 2010)
ENCH300: Chemical Process Thermodynamics (Spring 2009, Spring 2010)
BIOE120: Biology for Engineers (Spring 2011, Spring 2012, Spring 2013, Spring 2014)

Elective course: Metabolic Pathway Engineering

Metabolic Pathway Engineering (CHBE484; also listed as BIOE489L [undergrad] and ENCH648M [grad]) (Fall 2011, Fall 2012, Fall 2013, Fall 2014)

Fall 2014 schedule: MW 5:00 to 6:15, CHE 2136

The undergrad versions (CHBE484 and BIOE489L) will feature identical course objectives and grading schemes, whereas the grad version will feature advanced course objectives and a different grading scheme. CHBE484 satisfies the "significant biological content" criterion for CHBE electives.

Grading: Graded work will consist of two major exams (the first around mid-October, the second just before Thanksgiving break), a term project (assigned near the end of September, due around the last teaching day of the semester and presented during the final exam slot), five homework assignments (historically, homework assignments in this course has been assigned as teamwork) and class participation. There will be no test-type final exam.

Prerequisites: A working knowledge of (i) cell biology and (ii) matrix algebra, MATLAB and ordinary differential equations. Recommended preparatory courses are cell biology or biology for engineers (e.g. BSCI105 or BIOE120), kinetics/reaction engineering (e.g. CHBE440) and computer applications in (chemical or bio)engineering (e.g. CHBE250 or BIOE241).

Coverage: This course will cover the state-of-the-art in the area of metabolic engineering. This recent application of chemical engineering focuses on analyzing and engineering of metabolic pathways (sequences of chemical reactions in living organisms) for the benefit of humanity. Metabolic engineering is becoming increasingly popular in both industry and academia because it holds the promise of finding sustainable methods to manufacture fuels, chemicals, therapeutics and food for a growing world population. This class will cover both theory and applications of metabolic engineering: theory will include mathematical analysis of biological networks and the use of insights from such analyses toward engineering organisms to improve their performance, whereas applications will include metabolic engineering for biofuels and biorenewable chemical synthesis, synthetic biology and systems biology. Because metabolic engineering is a growing, dynamic field, the course will be significantly based on scholarly articles from scientific journals.

Inquiries may be directed to Dr. Sriram.

Research credits

To register for research credits through ENCH468 (undergraduate) or ENCH648, 799, 898 or 899 (graduate), please contact Dr. Sriram.