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Spectinomycin

Contents

Mode of Action

Spectinomycin is a bacteriostatic agent that inhibits translocation of the peptidyl tRNA from the A site to the P site.

Working Concentrations and Stock Solutions

Up to 100mg/mL stock concentration in H2O. 100ug/mL final concentration.

Resistance Gene

Mutations in rpsE, the S5 protein, prevent spectinomycin from binding.

Inhibiting protein synthesis