CHEM-ENG590E Wiki Textbook:Microcontact Printing: Difference between revisions

Cell-cell interactions may be studied using micropatterning techniques like printing. Bhatia et al. demonstrated microcontact printing allowed spatial control over liver cell populations, and thus allows a highly sophisticated method of investigation of cell growth, movement, shape, and death. In this study, collagen structures were immobilized under a patterned photoresist mask. The collagen then acted as an adhesive extracellular matrix for a patterning of hepatocytes and nonparenchymal cells. The heterotypic cell interactions in this microenvironment were then studied.