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DNA stability: Difference between revisions
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* Single stranded DNA deaminates significantly faster (> 100 times) than double stranded DNA | * Single stranded DNA deaminates significantly faster (> 100 times) than double stranded DNA | ||
* Mispaired Cs (C:C and T:C) are 1-2 orders of magnitude more likely to deaminate than in double stranded DNA (similar to single stranded DNA) | * Mispaired Cs (C:C and T:C) are 1-2 orders of magnitude more likely to deaminate than in double stranded DNA (similar to single stranded DNA) | ||
* The rate of deamination of C mispairs | * The rate of deamination of C mispairs is around <math>(8-40)\cdot 10^{-10}</math>/sec at 60C and about <math>(4-13)\cdot 10^{-10}</math>/sec at 37C | ||
==Strand cleavage== | ==Strand cleavage== | ||
