Uploads by Tanya E Raymond

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Date Name Thumbnail Size Description
11:46, 10 April 2013 Function of p53-dependent eRNAs.jpg (file) 23 KB Melo, C.A., et al., eRNAs are required for p53-dependent enhancer activity and gene transcription. Mol Cell, 2013. 49(3): p. 524-35.
08:36, 26 February 2013 Model for the Mechanism of Atl1-directed NER.jpg (file) 79 KB Model for the Mechanism of Atl1-directed NER Latypov, V. F., et al. (2012). "Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines." Mol Cell 47(1): 50-60.
08:28, 26 February 2013 Kinetic Characterization of Atl1 Affinity for ODNs.jpg (file) 141 KB Kinetic measurements of binding between Atl1 and ODN (A) Steady state kinetics using ELISA. Increased concentrations of Atl1 incubated with biotin tagged ODN bound to streptavidin microtiter plate.(B) IC50 values from the direct ELISA curves.(C) SPR sens
08:23, 26 February 2013 Crystal structures of Atl1 in complex with ODNs.jpg (file) 136 KB Crystal Structures for Atl1 in Complex with ODN Containing O6- HOEtG, O6-PrG, O6-BnG, or O6-CMG A. Structural overlay B. Molecular surface of Atl1 binding pocket C-F.Binding of O6-HOEtG (C, cyan), O6-PrG (D, green), O6-BnG (E, magenta), and O6-CMG (F, yel
11:45, 6 February 2013 Nature11676-f1.2.jpg (file) 129 KB A.) Yeast constructs. B.) Southern blot with induced arrest of replication fork. C.) Quantification of rearrangements Adapted from Figure 1 Mizuno, Ken’Ichi et al. Recombination-restarted replication makes inverted chromosome fusions at inverted repea
11:30, 6 February 2013 Supp fig replication restart repair.png (file) 88 KB Supplementary Figure Mizuno, Ken’Ichi et al. Recombination-restarted replication makes inverted chromosome fusions at inverted repeats. Nature 493, 246–249 (10 January 2013) doi:10.1038/nature11676
11:24, 6 February 2013 Recomb replication.png (file) 130 KB Supplementary Figure Mizuno, Ken’Ichi et al. Recombination-restarted replication makes inverted chromosome fusions at inverted repeats. Nature 493, 246–249 (10 January 2013) doi:10.1038/nature11676
19:37, 29 January 2013 Model of DSB Resection in Mammalian Cells.png (file) 23 KB Adapted from Figure 1 from Maria Pia Longhese et al. The EMBO Journal online publication 20 July 2010 doi:10.1038/emboj.2010.165
21:07, 20 January 2013 S2013.png (file) 54 KB Model for Resection of Neat DSBs in LSS and HSS FIgure 5 from Peterson, Shaun E. et al. Activation of DSB processing Requires Phosphorylation of CtIP by ATR. Molecular Cell In Press, Corrected Proof, Available online 27 December 2012.
12:06, 17 January 2013 384427 2328618022751 1468710201 32116370 1776786286 a.jpg (file) 17 KB