The Silva lab’s research efforts focus on the field of translation stem cell bioengineering.
Our research aim is to develop new material platforms that enable one to control stem/progenitor cell trafficking in the body.
The lab is focused on mastering chemistry and biologically inspired design principles that will result in the develop of new material platforms that enables one to actively negotiate biological barriers, including endothelial walls found in vascular networks.
Currently the research in the Silva lab is actively exploring and developing research on the following topics/research goals:
1. Develop tools for studying stem cell pluripotency and differentiation:
2. Development of new materials systems that locally define and regulate homing sites:
3. Design of a material system that provides the appropriate chemical and physical cues to control and manipulate endothelial cell extravasations:
4. Development of material systems that specifically target hypoxic regions in the body: