SPR Bibliography

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David Myszka and coworkers have published several annual reviews [1] about SPR and biosensor technologies in general.

Finding regeneration conditions

Andersson et al [2] described an efficient procedure for finding better chip regeneration conditions. The procedure samples diverse chemical space of reagents affecting intermolecular interactions and allows to formulate regeneration mixtures performing better then included ingridients alone.

Small molecule interactions



  1. Andersson K, Hämäläinen M, and Malmqvist M. Identification and optimization of regeneration conditions for affinity-based biosensor assays. A multivariate cocktail approach. Anal Chem. 1999 Jul 1;71(13):2475-81. DOI:10.1021/ac981271j | PubMed ID:10405611 | HubMed [andersson]
  2. Gossas T and Danielson UH. Analysis of the pH-dependencies of the association and dissociation kinetics of HIV-1 protease inhibitors. J Mol Recognit. 2003 Jul-Aug;16(4):203-12. DOI:10.1002/jmr.623 | PubMed ID:12898670 | HubMed [gossas03]
  3. Rich RL and Myszka DG. Survey of the year 2003 commercial optical biosensor literature. J Mol Recognit. 2005 Jan-Feb;18(1):1-39. DOI:10.1002/jmr.726 | PubMed ID:15549676 | HubMed [myzska03]

All Medline abstracts: PubMed | HubMed

J. Chem. Soc., Chem. Commun., 1990, 1526 - 1528, DOI: 10.1039/C39900001526 A novel hydrogel matrix on gold surfaces in surface plasmon resonance sensors for fast and efficient covalent immobilization of ligands (article on preparation of CM chip surface)