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Laboratory of Translational Genomics

Selected publications

Provenzani A, Fronza R, Loreni F, Pascale A, Amadio ML, Quattrone A. 2006. Global alterations in mRNA polysomal recruitment and deregulation of cap-dependent translation in a cell model of colorectal cancer progression to metastasis. Carcinogenesis 27: 1323-1333.

Ratti A, Fallini C, Cova L, Fantozzi R, Calzarossa C, Zennaro E, Pascale A, Quattrone A, Silani V. 2006. A role for the ELAV RNA binding proteins in neural stem cells: stabilization of the musashi-1 mRNA. J Cell Sci 119: 1442-1452.

Babini E, Bertini I, Capozzi F, Luchinat C, Quattrone A, Turano M. 2005. Principal Component Analysis of the Conformational Freedom within the EF-Hand Superfamily. J Proteome Res 4: 1961-1971.

Pascale A, Amadio M, Scapagnini G, Lanni C, Racchi M, Provenzani A, Govoni S, Alkon DL, Quattrone A. 2005. Neuronal ELAV proteins enhance mRNA stability by a PKC?-dependent pathway. Proc Natl Acad Sci USA 102: 12065-12070.

Banci L, Bertini I, Calderone V, Cramaro F, Del Conte R, Fantoni A, Mangani S, Quattrone A, Viezzoli MS. 2005. A prokaryotic superoxide dismutase paralog lacking two Cu ligands: From largely unstructured in solution to ordered in the crystal. Proc Natl Acad Sci USA 102: 7541-7546.

Pascale A, Gusev PA, Amadio M, Dottorini T, Govoni S, Alkon DL, Quattrone A. 2004. Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory. Proc Natl Acad Sci USA 101: 1217-1222.

Quattrone A, Pascale A, Nogues X, Zhao W, Gusev P, Pacini A, Alkon DL. 2001. Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins. Proc Natl Acad Sci USA 98: 11668-11673.

Quattrone A, Schiavone N, Rosini P, Donnini M, Lapucci A, Citti L, Bevilacqua A, Nicolin A, Capaccioli S. 2000. A conserved AU-rich element in the 3’ untranslated region of bcl-2 mRNA is endowed with destabilizing function that is involved in bcl-2 downregulation during apoptosis. FASEB J 14: 174-184.