Professor Philip Day - Publications

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  1. Ayers D, Clements DN, Day PJR. Expression stability of commonly used control genes in canine articular connective tissues Osteoarthritis and Cartilage. Accepted April 2007.
  2. Brown JJ, Ollier WE, Arscott G, Xiaya Ke, Lamb J, Day P, Bayat A. Genetic Susceptibility to Keloid Scarring: SMAD gene Frequencies in Jamaicans: (Submitted to Journal of experimental Dermatology May 2007 – under review)
  3. Day PJR. Specific detection of bacterial pathogens using oligonucleotide microarrays generated from hydrolysis PCR probe sequences. Microarrays; Methods and Protocols, Second Edition Editor, Rampal B. Methods in Molecular Biology. The Humana Press Inc, 2007 (In press).
  4. Day PJR, Manz A. Old questions, new analytes and the arrival of integrated quantitative clinical diagnosis. Nature Biotechnology. In review.
  5. Clements DN, Carter SD, Innes JF, Ollier WER, Day PJR. Gene expression profiling of normal and ruptured canine anterior cruciate ligaments. Osteoarthritis and Cartilage. Accepted 2007.
  6. Giger T, Amstutz U, Excoffier L, Champigneulle A, Day PJR, Powell R, Largiadèr CR. The genetic basis of smoltification: Functional genomics tools facilitate the search for the needle in the haystack. In: Sea Trout: Biology Conservation and Management eds. Harris G, Millner NJ. Blackwell, London. 2007.
  7. Maccoux L, Salway F, Day PJR, Clements D. Expression profiling of select cytokines canine osteoarthritis tissues. Veterinary Immunology and Immunopathology. Accepted April 2007.
  8. Mohr S, Zhang Y-H, Macaskill A, Day PJR, Barber RW, Goddard NJ, Emerson DR, Fielden PR. Numerical and experimental study of a chip for PCR in droplets. J of Microfludics and Nanofluidics. Accepted, 2007.
  9. Prest JE, Baldock SJ, Day PJ, Fielden PR, Goddard NJ, Treves Brown BJ. Miniaturised isotachophoresis of DNA. J Chromatogr A. 2007 Jan 12; epub ahead of print.


  1. Amstutz U, Giger T, Champigneulle A, Day PJR, Largiadèr CR. Distinct temporal patterns of Transaldolase 1 gene expression in future migratory and sedentary brown trout (Salmo trutta). Aquaculture 260: 326-336, 2006.
  2. Chen L, Prest JE, Fielden PR, Goddard NJ, Manz A, Day PJR. Miniaturised isotachophoresis analysis. Lab Chip. 6(4):474-87, 2006.
  3. Clements DN, Carter SD, Innes JF, Ollier WER, Day PJR. Analysis of normal and osteoarthritic canine cartilage mRNA expression by quantitative polymerase chain reaction. Arthritis Research and Therapy 8: R158. 2006.
  4. Day PJR. Miniaturization applied to analysis of nucleic acids in heterogeneous samples. Expert Rev. Mol. Diag. 6(1), 23-28, 2006.
  5. Giger T, Excoffier L, Day PJR, Champigneulle A, Hansen MM, Powell R, Largiadèr CR.Life history shapes gene expression in salmonids. Current Biology. Available on line R281-R262, 2006.
  6. Lux A, Salway F, Dressman HK, Kröner-Lux G, Hafner M, Day PJR, Marchuk DA, Garland J. ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF- and constitutively active receptor induced gene expression. BMC Cardiovascular Disorders. 6:13. 2006.
  7. Mohr S, Zhang YH, Macaskill A, Day PJR, Barber RW, Goddard NJ, Emerson DR, Fielden PR. Optimal Design and Operation for a droplet-based PCR chip. Proceedings of ASME ICNMM2006 4th International conference of Nanochannels, Microchannels and Minichannels. 2006, Limmerick, Ireland.
  8. Salway F, Day PJR, Ollier WER, Peakman T. 5’ RNA Tags present in plasma and buffy coat from EDTA blood assessed by qPCR. Int J Epidemiol. Submitted October 2006.


  1. Mohammadi M, Day PJR, Ollier WER, Data S, Yonan N, Hutchinson IV. Investigation on VEGF splice variants in PBMCs and heart transplants by semi-quantitative RT-PCR and TaqMan real-time PCR. Int J Immunogenetics, 32: 263, 2005.


  1. Auroux PA, Koc Y, deMello A, Manz A, Day PJR. Miniaturised nucleic acid analysis. Lab on a Chip, 4: 534-546, 2004.
  2. Greiner O, Day PJR. Oligonucleotide microarrays generated from hydrolysis polymerase chain reaction probe sequences. Anal Biochem. 334: 197-203, 2004.
  3. Hoerndli F, Toïgo M, Schild A, Götz J, Day PJR. Reference genes identified in SH-SY5Y cells using custom-made gene-arrays with validation by quantitative polymerase chain reaction. Anal Biochem 335: 30-41, 2004.#Mohammadi M, Day PJR. Oligonucleotides used as template calibrators for general application in quantitative polymerase chain reaction. Anal Biochem 335: 299-304, 2004.
  4. Marty A, Greiner O, Day PJR, Gunziger S, Mühlemann K, Nadal D. Detection of Haemophilus influenzae type b by Real-Time PCR. J Clin Microbiol . 42: 3813-3815, 2004.


  1. Auroux P-A, Niggli FK, Manz A, Day PJR. PCR microfluidics device for detection of low copy number nucleic acids. Nanotech 1: 55-58, 2003.
  2. Day PJR. The relationship between the NMYC proto-oncogene and the neuroblastoma transcriptome. Chimia 57: 19, 2003.
  3. Greiner O, Day PJR, Altwegg M, Nadal D. Quantitative detection of Moraxella catarrhalis in nasopharyngeal secretions by real-time PCR. J Clin Microbiol. 41: 1386-90, 2003.


  1. Greiner O, Berger C, Day PJR, Meier G, Tang CM, Nadal D. Rates of Detection of Neisseria meningitidis in tonsils differ in relation to local incidence of invasive disease. J Clin Microbiol 40: 3917-3921, 2002.


  1. Berger C, Day P, Meier G, Zingg W, Bossart W, Nadal D. Dynamics of Epstein-Barr virus (EBV) DNA levels in serum during EBV-associated disease. J Med Virol 64: 505-12, 2001. (Pfizer prize, February 2002)
  2. Greiner O, Day, PJR, Bosshard PP, Imeri F, Altwegg M, Nadal D. Quantitative detection of Streptococcus pneumoniae in nasopharyngeal secretions by real-time PCR. J Clin Microbiol 39: 3129-3134, 2001.


  1. Watanabe TK, Bihoreau M-T….Day PJ et al. A radiation hybrid map of the rat genome containing 5,255 markers. Nature Genetics 22: 27-36 May, 1999.


  1. Deloukas P, GD Schuler… Day PJ et al. A physical map of 30,000 human genes. Science 282: 744-746, 1998.


  1. Schuler GD, Boguski MS....Day PJ et al. A gene map of the human genome. Science 274: 540-546, 1996.
  2. Weinreb M, Day PJR, Nyongo A, Riyat MS, Othieno-Abinya NA, Raafat F, Mann JR. Consistent association between Epstein-Barr Virus and childhood Hodgkin's disease in Kenya. Blood 87: 3828-3836, 1996.
  3. Weinreb M, Day PJR, Niggli FK, Powell J, Raafat F, Hesseling PB, Schneider JW et al. The role of EBV in Hodgkin's disease in children from different geographical areas. Archives of Childhood Diseases 74: 27-31, 1996.


  1. Weinreb M, Day PJR, Niggli FK, Raafat F, Mann JR. BCL-2 oncoprotein in neuroblastoma. Lancet, (345): 15th April, 1995.


  1. Weinreb M, Niggli FK, Day PJR, Stevens, Mann JR. Prevalence of monosomy 18 in childhood Hodgkin's disease. Clin Oncol 6: 193-194, 1994.


  1. Smith C, Day PJR, Walker MR. Generation of cohesive ends on PCR products by UDG-mediated excision of dU, and application for cloning into restriction digest-linearized vectors. PCR Meths and Applic 2: 328-332, 1993.


  1. Day PJR, Walker MR. Sequencing self-ligated PCR products using 3' over-hangs generated by specific cleavage of dUTP by uracil DNA glycosylase. Nucleic Acids Res 19: 6959, 1991.
  2. Day PJR, Flora PS, Fox JE, Walker MR. Immobilisation of polynucleotides to magnetic particles: factors influencing hybridisation efficiency. Biochem J 278: 735-740, 1991.
  3. Green EK, Bain SC, Day PJR, Barnett AH, Charleson F, Jones AF, Walker MR. Detection of human apolipoprotein E3, E2 and E4 genotypes using allele specific oligonucleotide primed polymerase chain reaction assays: development and validation. Clin Chem. 37: 1263-1268, 1991.
  4. Bevan IS, Daw R, Day PJR, Ala FA, Walker MR. Evaluation of human CMV infection in a blood donor population by the polymerase chain reaction. Br J Haem 78: 94-99, 1991.


  1. Day PJR, Bevan IS, Gurney SJ, Young LS,Walker MR. In vitro synthesis and application of biotinylated DNA probes for human HPV16 utilising polymerase chain reaction. Biochem J 267: 119- 123, 1990.


  1. Sweeney G, Brooks A, Day PJR, Old RW. DNA sequence of the first exon and 5' flanking region of the 68K serum albumin gene of Xenopus laevis. Nucl Acids Res 15: 5889, 1987.