Moore Notes 4 23 14

Group Call

• Participants: Jonathan, Katie, Tom, Donying, Guillaume, Josh, Stacia, Ladan, Sarah, Patrick

• May meeting planning
  • Date: Thursday, May 8
  • Samantha Forde can attend 10:30-2:30pm
  • Topic brainstorming:
    • Progress and Future tangibles: software, deliverables, research results
      • Unfinished work and what we need to obtain to answer them
    • Aquatic, terrestrial?, and marine interface
    • Open and emerging analytical challenges in our field(s)
    • What questions can we address with the data that is available?
      • Concrete plan of action
    • Should we be generating data?
    • Use of simulations
    • Temporal variation analysis
    • Biodiversity hotspots from a functional perspective
    • New metabolic pathways across environmental samples
    • Network algorithm analysis to look at a higher level agglomeration of data
    • Impact of new sequencing technologies on future informatics and sampling (PacBio, Moleculo, MinION vs. assemblies from short reads)
      • Assemblies get confused if abundant organisms have lots of polymorphism
      • Information gleaned from rare organisms benefits from having a few long reads
      • Is streaming sequencing possible? Maybe.
        • Library prep becomes the rate limiting step
        • Algorithms for dealing with data coming in at this rate
  • Organization:
    • First part: progress, new directions, challenges
    • Second part: topics where we're trying to solve specific problems (other than data availability, e.g., whole genome analysis, networks, phylogeography)