Moore Notes 11 9 15

PI Call

• Participants: Jonathan, Tom, Jonathan

• Future Funding
  • Tom Pew application
  • NIH postdoc salaries
  • Training grants

• Ongoing work
  • JE supporting informatics people on other grants currently
    • Can test methods on specific systems (e.g., seagrass metagenomes, rice, corn - not 16S)
      • Eisen lab people are applying it now and will follow up on these and Tara Oceans
    • Guillaume, Ladan, Dongying might be able to contribute more broadly while working on other projects
      • Dongying is on Geneology of Life single cell grant, doing some low-pass metagenomic sequencing of marine environments
  • Tom wants to contribute towards a marine niche modeling application
    • No available informatics staff currently
    • NSF proposal is main thrust right now (mostly 16S right now)

• What would it take to move Tara Oceans analysis forward?
  • ShotMAP community level analyses
  • PhyloCNV strain level analyses of prevalent species
  • Eisen lab can test methods and learn to use them
  • Tom suggests list of objectives and who is responsible
  • High priority gene/pathway/function list for focused analyses (versus diversity)

• Further towards future
  • Interfacing with Curtis Huttenhower, Titus Brown, Brett Tyler
  • Using metagenomics to
    • improve genome-based protein databases
    • annotate novel proteins
    • But requires different resources than what we have (libraries could lead this or iPlant as example)