Matt Gethers/20.380 HIV Project/Technical Paper/IP Outline

Timeline for Development & Conclusion

We will seek an initial round of funding to do initial in vitro and in vivo experiments
After drug is approved we will begin treating first-world patients who can afford the initially expensive treatment
Simultaneously we will begin developing the same approach to treat other viral diseases such as the various hepatitis viruses
We will seek patients’ and possibly non-infected blood donors to consent to us storing their engineered hematopoietic stem cells for future use in creating a library of stem cells
- This will remove the necessity of drawing a patient's blood to generate patient-specific stem cells, lowering costs
Once we show our treatment is financially feasible, we will actively seek out funding from NGOs to expand our scope and begin treatment in third-world countries
Our reservoir of HSCs and experience in treating first-world patients will reduce the cost of treating patients in the third-world enough to provide treatment to everyone

We will probably have to license the Glaser patent since it covers so much of our idea
We will first attempt to purchase the exclusive rights to his patent for $XXX
If that does not work, we will offer him a 25% (?) share of our equity and a position on our scientific advisory board
The novel part of our idea is the use of stem cells to generate erythrocyte viral traps, and we will try to patent this aspect