Matt Gethers/20.380 HIV Project/Papers

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Origin of blood

Changing modified regions in the genome in hematopoietic stem cell differentiation

Inhibition of Plasmodium falciparum proliferation in vitro by double-stranded RNA directed against malaria histone deacetylase

Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency

Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo

Hematopoietic Stem Cell Tracking In Vivo: A Comparison of Short-Term and Long-Term Repopulating Cells

Factors that influence collection and engraftment of autologous peripheral-blood stem cells

Important: Autologous peripheral hematopoietic stem cell transplantation restores hematopoietic function following marrow ablative therapy

Important: Peripheral Blood Stem Cells for Allogeneic Transplantation: A Review

CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1

Phenotypic and functional evidence for the expression of CD4 by hematopoietic stem cells isolated from human fetal liver

The Biology of Hematopoietic Stem Cells

Human Immunodeficiency Virus Type 1 Vectors Efficiently Transduce Human Hematopoietic Stem Cells

Complementation of murine cells for human immunodeficiency virus envelope/CD4-mediated fusion in human/murine heterokaryons

Mice transgenic for human CD4 and CCR5 are susceptible to HIV infection

Specific expression of the human CD4 gene in mature CD4+ CD8- and immature CD4+ CD8+ T cells and in macrophages of transgenic mice.

Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response

Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome

AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression

A ligand-receptor signaling threshold model of stem cell differentiation control: a biologically conserved mechanism applicable to hematopoiesis

Differentiation and proliferation of hematopoietic stem cells

Hematopoietic stem cell aging is associated with functional decline and delayed cell cycle progression

  1. Bensinger WI, Clift RA, Anasetti C, Appelbaum FA, Demirer T, Rowley S, Sandmaier BM, Torok-Storb B, Storb R, and Buckner CD. Transplantation of allogeneic peripheral blood stem cells mobilized by recombinant human granulocyte colony stimulating factor. Stem Cells. 1996 Jan;14(1):90-105. DOI:10.1002/stem.140090 | PubMed ID:8820955 | HubMed [Bensinger]
  2. Berson JF, Long D, Doranz BJ, Rucker J, Jirik FR, and Doms RW. A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains. J Virol. 1996 Sep;70(9):6288-95. PubMed ID:8709256 | HubMed [Berson]
  3. Blum MD, Wong GT, Higgins KM, Sunshine MJ, and Lacy E. Reconstitution of the subclass-specific expression of CD4 in thymocytes and peripheral T cells of transgenic mice: identification of a human CD4 enhancer. J Exp Med. 1993 May 1;177(5):1343-58. PubMed ID:8097522 | HubMed [Blum]
  4. Buza-Vidas N, Luc S, and Jacobsen SE. Delineation of the earliest lineage commitment steps of haematopoietic stem cells: new developments, controversies and major challenges. Curr Opin Hematol. 2007 Jul;14(4):315-21. DOI:10.1097/MOH.0b013e3281de72bb | PubMed ID:17534155 | HubMed [Buza]
  5. Chelucci C, Casella I, Federico M, Testa U, Macioce G, Pelosi E, Guerriero R, Mariani G, Giampaolo A, Hassan HJ, and Peschle C. Lineage-specific expression of human immunodeficiency virus (HIV) receptor/coreceptors in differentiating hematopoietic precursors: correlation with susceptibility to T- and M-tropic HIV and chemokine-mediated HIV resistance. Blood. 1999 Sep 1;94(5):1590-600. PubMed ID:10477684 | HubMed [Chelucci]
  6. Dragic T, Picard L, and Alizon M. Proteinase-resistant factors in human erythrocyte membranes mediate CD4-dependent fusion with cells expressing human immunodeficiency virus type 1 envelope glycoproteins. J Virol. 1995 Feb;69(2):1013-8. PubMed ID:7815477 | HubMed [Dragic]
  7. Federsppiel B, Melhado IG, Duncan AM, Delaney A, Schappert K, Clark-Lewis I, and Jirik FR. Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleen. Genomics. 1993 Jun;16(3):707-12. DOI:10.1006/geno.1993.1251 | PubMed ID:8325644 | HubMed [Federsppiel]
  8. Feng Y, Broder CC, Kennedy PE, and Berger EA. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science. 1996 May 10;272(5263):872-7. PubMed ID:8629022 | HubMed [Feng]
  9. Hammache D, Yahi N, Maresca M, Piéroni G, and Fantini J. Human erythrocyte glycosphingolipids as alternative cofactors for human immunodeficiency virus type 1 (HIV-1) entry: evidence for CD4-induced interactions between HIV-1 gp120 and reconstituted membrane microdomains of glycosphingolipids (Gb3 and GM3). J Virol. 1999 Jun;73(6):5244-8. PubMed ID:10233996 | HubMed [Hammache]
  10. Kessinger A, Armitage JO, Landmark JD, Smith DM, and Weisenburger DD. Autologous peripheral hematopoietic stem cell transplantation restores hematopoietic function following marrow ablative therapy. Blood. 1988 Mar;71(3):723-7. PubMed ID:2894230 | HubMed [Kessinger]
  11. Komor M, Güller S, Baldus CD, de Vos S, Hoelzer D, Ottmann OG, and Hofmann WK. Transcriptional profiling of human hematopoiesis during in vitro lineage-specific differentiation. Stem Cells. 2005 Sep;23(8):1154-69. DOI:10.1634/stemcells.2004-0171 | PubMed ID:15955831 | HubMed [Komor]
  12. Krishnamoorthy L, Bess JW Jr, Preston AB, Nagashima K, and Mahal LK. HIV-1 and microvesicles from T cells share a common glycome, arguing for a common origin. Nat Chem Biol. 2009 Apr;5(4):244-50. DOI:10.1038/nchembio.151 | PubMed ID:19234452 | HubMed [Krishnamoorthy]
  13. Lee NS and Rossi JJ. Control of HIV-1 replication by RNA interference. Virus Res. 2004 Jun 1;102(1):53-8. DOI:10.1016/j.virusres.2004.01.015 | PubMed ID:15068880 | HubMed [Lee]
  14. Lee V, Li CK, Shing MM, Chik KW, Li K, Tsang KS, Zhao DC, Lai DH, Wong A, and Yuen PM. Single vs twice daily G-CSF dose for peripheral blood stem cells harvest in normal donors and children with non-malignant diseases. Bone Marrow Transplant. 2000 May;25(9):931-5. DOI:10.1038/sj.bmt.1702338 | PubMed ID:10800059 | HubMed [LeeV]
  15. Li MJ, Kim J, Li S, Zaia J, Yee JK, Anderson J, Akkina R, and Rossi JJ. Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy. Mol Ther. 2005 Nov;12(5):900-9. DOI:10.1016/j.ymthe.2005.07.524 | PubMed ID:16115802 | HubMed [Li]
  16. Lie AK and To LB. Peripheral Blood Stem Cells: Transplantation and Beyond. Oncologist. 1997;2(1):40-49. PubMed ID:10388028 | HubMed [Lie]
  17. Moore JP, Trkola A, and Dragic T. Co-receptors for HIV-1 entry. Curr Opin Immunol. 1997 Aug;9(4):551-62. PubMed ID:9287172 | HubMed [Moore]
  18. Ogawa M. Differentiation and proliferation of hematopoietic stem cells. Blood. 1993 Jun 1;81(11):2844-53. PubMed ID:8499622 | HubMed [Ogawa]
  19. Orkin SH. Diversification of haematopoietic stem cells to specific lineages. Nat Rev Genet. 2000 Oct;1(1):57-64. DOI:10.1038/35049577 | PubMed ID:11262875 | HubMed [Orkin]
  20. Orkin SH and Zon LI. Hematopoiesis: an evolving paradigm for stem cell biology. Cell. 2008 Feb 22;132(4):631-44. DOI:10.1016/j.cell.2008.01.025 | PubMed ID:18295580 | HubMed [Orkin2]
  21. Orlic D, Fischer R, Nishikawa S, Nienhuis AW, and Bodine DM. Purification and characterization of heterogeneous pluripotent hematopoietic stem cell populations expressing high levels of c-kit receptor. Blood. 1993 Aug 1;82(3):762-70. PubMed ID:7687891 | HubMed [Orlick]
  22. Shizuru JA, Jerabek L, Edwards CT, and Weissman IL. Transplantation of purified hematopoietic stem cells: requirements for overcoming the barriers of allogeneic engraftment. Biol Blood Marrow Transplant. 1996 Feb;2(1):3-14. PubMed ID:9078349 | HubMed [Shizuru]
  23. ter Brake O, 't Hooft K, Liu YP, Centlivre M, von Eije KJ, and Berkhout B. Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition. Mol Ther. 2008 Mar;16(3):557-64. DOI:10.1038/ | PubMed ID:18180777 | HubMed [ter]
  24. Swiers G, Patient R, and Loose M. Genetic regulatory networks programming hematopoietic stem cells and erythroid lineage specification. Dev Biol. 2006 Jun 15;294(2):525-40. DOI:10.1016/j.ydbio.2006.02.051 | PubMed ID:16626682 | HubMed [Swiers]
  25. Valente ST, Gilmartin GM, Mott C, Falkard B, and Goff SP. Inhibition of HIV-1 replication by eIF3f. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4071-8. DOI:10.1073/pnas.0900557106 | PubMed ID:19237569 | HubMed [Valente]
  26. Waskow C, Madan V, Bartels S, Costa C, Blasig R, and Rodewald HR. Hematopoietic stem cell transplantation without irradiation. Nat Methods. 2009 Apr;6(4):267-9. DOI:10.1038/nmeth.1309 | PubMed ID:19270698 | HubMed [Waskow]
All Medline abstracts: PubMed | HubMed