Kirk:Publications

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2020

Stachowski MJ, Zlobin A,Papadaki M, Perez E, Martin JL, Aima Muntu N, Moravec CS, Kirk J.A. An Independent Pool of GSK-3β Modulates Calcium Sensitivity at the Cardiac Myofilament. Biophysical Journal 118(3), 592a-593a. Link

Papadaki M, Kampaengsri T, Bonomo R, White C, Aubert V, Aubert G, Campbell S, Kirk J.A. Molecular Mechanisms and Therapeutic Approaches of Myofilament Glycation as a Result of Diabetes. Biophysical Journal 118 (3), 327a. Link

2019

Kirk JA, de Boer R. Moving galectin-3 closer to the goal line. American Journal of Physiology Heart and Circulatory Physiology. Link

2018

Rattanasopa C, Kirk JA, Bupha-Intr T, Papadaki M, de Tombe P, Wattanapermpool J. Estrogen but not testosterone preserves myofilament function from doxorubicin-induced cardiotoxicity by reducing oxidative modifications. American Journal of Physiology Heart and Circulatory Physiology. Link

Papadaki M, Holewinski RJ, Previs S, Martin T, Stachowski MJ, Amy Li, Blair C, Moravec C.S, Van Eyk,Kenneth JE, Campbell KS, Warshaw DM, Kirk JA.Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function. JCI Insight, 2018; 3(20). Link

Stachowski M.J, Holewinski R.J, Grote E, Van Eyk JE, Kirk J.A. Phospho-Proteomic Analysis of Cardiac Dyssynchrony and Resynchronization Therapy. Proteomics. Link

Kirk J.A, Frangogiannis NG.Galectin-3 in the pathogenesis of heart failure: a causative mediator or simply a biomarker?AJP: Heart and Circulatory Physiology. Link


2017

Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA.Right Ventricular Myofilament Functional Differences in Humans With Systemic Sclerosis-Associated Versus Idiopathic Pulmonary Arterial Hypertension. Circulation. Link

Rabek MJ, Stachowski MJ, Kirk JA, Willis MS. The role of heat shock proteins and co-chaperones in heart failure. Philosophical Transactions B. Link

Sonaglioni A, Baravelli M, Lombardo M, Sommese C, Anzà C, Kirk JA, Padeletti L.Ventricular-arterial coupling in centenarians without cardiovascular diseases.Link


2016

Ngkelo A, Richart A, Kirk J.A, Bonnin P, Vilar, Lemitre M, Marck P, Branchereau M, Le Gall S, Renault N, Coralie Guerin C, Ranek MJ, Kervadec A, Danelli L, Gautier G,Blank U, Launay P,Camerer E, Bruneval P, Menasche P,Heymes C, Luche E, Casteilla L, Cousin B, Rodewald HR, Kass DA, Silvestre J.S. Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction.Journal of Experimental Medicine. Link

Kirk J.A, Holewinski R.J, Crowgey E.L,Van Eyk J.E. Protein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials. Proteomics. Link

Kirk J.A, Cingolani O.H.Thrombospondins in the transition from myocardial infarction to heart failure. Journal of Molecular and Cellular Cardiology. Link


2015

Kirk J.A, Chakir1 K, Lee K.H,*,Karst E, Holewinski RJ, Pironti G, Tunin1 RS, Pozios I, Abraham T.P, de Tombe P, Rockman H.A, Van Eyk1 J.E, Craig R, Farazi T.G, Kass D.A.Pacemaker-induced transient asynchrony suppresses heart failure progression. Science Translational Medicine. Link

Kirk J.A, Kass D.A. Cellular and Molecular Aspects of Dyssynchrony and Resynchronization. Cardiac Electrophysiology Clinics. Elsevier. Link

Fert-Bober J, Giles J.T, Holewinski R.J, Kirk J.A, Uhrigshardt H, Crowgey E.L, Andrade F, Bingham C.O III, Jin Kyun Park, Halushka M.K, Kass D.A, Bathon J.M, Van Eyk J.E. Citrullination of myofilament proteins in heart failure. Cardiovascular Research. Link

Lee D.I, Zhu G, Sasaki T, Cho G, Hamdani N, Holewinski R, Jo S-H, Danner T, Zhang M, Rainer P.P, Bedja D, Kirk J.A, Ranek M.J, Dostmann W.R, Kwon C, Margulies K.B, Van Eyk J.E, Paulus W.J, Takimoto E & Kass D.A. Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease. Nature 519, 472–476 (2015). Link


Previous Kirk Publications


Kirk JA, Paolocci N. New redox-related arrows in the arsenal of cardiac diseases treatment. Antioxidant and Redox Signaling, 2014; 21(14): 1945-1948, PMID:25211226

Kirk JA, Kass DA. Electromechanical Dyssynchrony and Resynchronization of the Failing Heart. Circulation Research, 2013, Aug 30; 113(6): 765-76, PMID: 23989718, PMCID:PMC3874431

Kirk JA, Saccomani MP, Shroff SG. A Priori Identifiability Analysis of Cardiovascular Models. Cardiovascular Engineering and Technology, 2013: 4(4): 500-512, PMCID:PMC4696755