Kirk:Publications
2020
Stachowski MJ, Zlobin A,Papadaki M, Perez E, Martin JL, Aima Muntu N, Moravec CS, Kirk J.A.
An Independent Pool of GSK-3β Modulates Calcium Sensitivity at the Cardiac Myofilament. Biophysical Journal 118(3), 592a-593a.
Link
Papadaki M, Kampaengsri T, Bonomo R, White C, Aubert V, Aubert G, Campbell S, Kirk J.A. Molecular Mechanisms and Therapeutic Approaches of Myofilament Glycation as a Result of Diabetes. Biophysical Journal 118 (3), 327a. Link
2019
Kirk JA, de Boer R. Moving galectin-3 closer to the goal line.
American Journal of Physiology Heart and Circulatory Physiology. Link
2018
Rattanasopa C, Kirk JA, Bupha-Intr T, Papadaki M, de Tombe P, Wattanapermpool J. Estrogen but not testosterone preserves myofilament function from doxorubicin-induced cardiotoxicity by reducing oxidative modifications. American Journal of Physiology Heart and Circulatory Physiology. Link
Papadaki M, Holewinski RJ, Previs S, Martin T, Stachowski MJ, Amy Li, Blair C, Moravec C.S, Van Eyk,Kenneth JE, Campbell KS, Warshaw DM, Kirk JA.Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function. JCI Insight, 2018; 3(20). Link
Stachowski M.J, Holewinski R.J, Grote E, Van Eyk JE, Kirk J.A. Phospho-Proteomic Analysis of Cardiac Dyssynchrony and Resynchronization Therapy. Proteomics.
Link
Kirk J.A, Frangogiannis NG.Galectin-3 in the pathogenesis of heart failure: a causative mediator or simply a biomarker?AJP: Heart and Circulatory Physiology.
Link
2017
Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA.Right Ventricular Myofilament Functional Differences in Humans With Systemic Sclerosis-Associated Versus Idiopathic Pulmonary Arterial Hypertension. Circulation. Link
Rabek MJ, Stachowski MJ, Kirk JA, Willis MS. The role of heat shock proteins and co-chaperones in heart failure. Philosophical Transactions B.
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Sonaglioni A, Baravelli M, Lombardo M, Sommese C, Anzà C, Kirk JA, Padeletti L.Ventricular-arterial coupling in centenarians without cardiovascular diseases.Link
2016
Ngkelo A, Richart A, Kirk J.A, Bonnin P, Vilar, Lemitre M, Marck P, Branchereau M, Le Gall S, Renault N, Coralie Guerin C, Ranek MJ, Kervadec A, Danelli L, Gautier G,Blank U, Launay P,Camerer E,
Bruneval P, Menasche P,Heymes C, Luche E, Casteilla L, Cousin B, Rodewald HR, Kass DA, Silvestre J.S. Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction.Journal of Experimental Medicine. Link
Kirk J.A, Holewinski R.J, Crowgey E.L,Van Eyk J.E. Protein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials. Proteomics. Link
Kirk J.A, Cingolani O.H.Thrombospondins in the transition from myocardial infarction to heart failure. Journal of Molecular and Cellular Cardiology. Link
2015
Kirk J.A, Chakir1 K, Lee K.H,*,Karst E, Holewinski RJ, Pironti G, Tunin1 RS, Pozios I, Abraham T.P, de Tombe P, Rockman H.A, Van Eyk1 J.E, Craig R, Farazi T.G, Kass D.A.Pacemaker-induced transient asynchrony suppresses heart failure progression. Science Translational Medicine. Link
Kirk J.A, Kass D.A. Cellular and Molecular Aspects of Dyssynchrony and Resynchronization. Cardiac Electrophysiology Clinics. Elsevier. Link
Fert-Bober J, Giles J.T, Holewinski R.J, Kirk J.A, Uhrigshardt H, Crowgey E.L, Andrade F, Bingham C.O III, Jin Kyun Park, Halushka M.K, Kass D.A, Bathon J.M, Van Eyk J.E. Citrullination of myofilament proteins in heart failure. Cardiovascular Research. Link
Lee D.I, Zhu G, Sasaki T, Cho G, Hamdani N, Holewinski R, Jo S-H, Danner T, Zhang M, Rainer P.P, Bedja D, Kirk J.A, Ranek M.J, Dostmann W.R, Kwon C, Margulies K.B, Van Eyk J.E, Paulus W.J, Takimoto E & Kass D.A. Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease. Nature 519, 472–476 (2015). Link
Previous Kirk Publications
Kirk JA, Paolocci N. New redox-related arrows in the arsenal of cardiac diseases treatment. Antioxidant and Redox Signaling, 2014; 21(14): 1945-1948, PMID:25211226
Kirk JA, Kass DA. Electromechanical Dyssynchrony and Resynchronization of the Failing Heart. Circulation Research, 2013, Aug 30; 113(6): 765-76, PMID: 23989718, PMCID:PMC3874431
Kirk JA, Saccomani MP, Shroff SG. A Priori Identifiability Analysis of Cardiovascular Models. Cardiovascular Engineering and Technology, 2013: 4(4): 500-512, PMCID:PMC4696755