Kevin Janes

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Kevin Janes (BE doctoral), in collaboration with Prof. Michael Yaffe (Biology / BE, MIT), Prof. Peter Sorger (Biology / BE, MIT)

Studies of intracellular signaling networks and their quantitative influence on cell behavior; emphasis on apoptosis-versus-survival of epithelial cells in response to cytokines (TNF, insulin, EGF). Multivariate, data-driven modeling of signal transduction and correlation with cellular outcome.

UROP's: Lili Peng-analysis of protein kinase phosphorlyation state by quantitative Western blotting; Brian Chase-in vitro stimulation and sample preparation for cell signaling studies.