Kafatos:Tan, Lee Aun
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Lee Aun Tan Division of Cell & Molecular Biology,
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RESEARCH INTERESTS
My current postdoctoral research interest focuses on the participation of CLIP-serine proteases in the melanization of Plasmodium berghei in Anopheles gambiae. I have explored the use of recombinant proteins and various protease assays to assess the contribution of the various CLIP-serine proteases to the clearance and melanization of the parasite. The interaction of the mosquito immune system upon bacterial challange has also been explored and given that the immune system of an invertebrate is wholly innate, it was not surprising that many components of the immune cascade mediated by the CLIP-serine proteases function very similarly in the bacterial system.
EDUCATION
1996 B.Sc with Merit, Cell & Molecular Biology and Plant Biology, Deprtment of Biological Sciences, National University of Singapore
1997 B.Sc (Hons), Cell & Molecular Biology, Department of Biological Sciences, National University of Singapore
1998 M.Sc Integrative Bioscience, Department of Zoology, University of Oxford
2002 D.Phil Biochemistry, MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford
PREVIOUS APPOINTMENTS
2003 - 2005 Arthritis Research Campaign (ARC) Research Fellow, Gastroenterology and Autoimmunity Unit, Institute of Child Health, University College London
2006 - 2007 Coeliac UK Fellowship, Institute of Child Health, Gastroenterology and Autoimmunity Unit, University College London
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