Jesse Macadangdang

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Researching the role of mechanical substrate cues on stem cell derived cardiomyocyte (SC-CM) functional maturation. Specifically investigating the impact of nanotopography on the electrophysiological function of SC-CMs in order to develop a more in vivo-like tissue for in vitro screening purposes.

Honors and Awards

NSF Graduate Research Fellowship Honorable Mention (2011); Graduated with High Distinction from the University of Virginia (2011); Tau Beta Pi National Engineering Honor Society (2010 – Present)

Published Work

Macadangdang J, Jiao A, Carson D, Regnier M, Kim DH. (Forthcoming). A Scalable, Nanotopographically-Defined Model of Myocardium Mimicking the In Vivo Ventricular Organization. Journal of Visualized Experiments.

Trosper N, Kerscher P, Macadangdang J, Carson D, Jiao A, Lipke E, Kim DH. (Forthcoming). Micro- and Nanofabrication Approaches to Cardiac Tissue Engineering. Tissue and Organ Regeneration: Advances in Micro- and Nanotechnology.

BMES Annual Meeting Poster Presentation: Fall 2010 Title: Computational Study of Infarct Reinforcement and Its Impact on Left Ventricular Function

Fomovsky GM, Macadangdang JR, Ailawadi G, Holmes JW. (2011). Model-Based Design of Mechanical Therapies for Myocardial Infarction. Journal of Cardiovascular Translational Research.

Kortsmit J, Davies NH, Miller R, Macadangdang J, Zilla P, Franz T. (2011). The Effect of Hydrogel Injection On Cardiac Function and Myocardial Mechanics in a Computational Post Infarct Heart Model. Computer Methods in Biomechanics and Biomedical Engineering.

Macadangdang JR, et al. Computational Study of Functional Impact of Hydrogel Injection into Post-Infarct Scar Tissue [abstract]. In: AfriCOMP11. Jan. 5–8, 2011. Cape Town, South Africa.