IGEM:Stanford/2009/Oxidative Stress

Project Summary

Not defined yet.

What We Know

• In high intensity light, wild type cyanobacteria downregulate Photosystem I [1].
• The mutant pmgA cannot downregulate Photosystem I in high intensity light [1].
• pmgA mutants initially grow well in high intensity light (better than wild type) but after 48 hours they succumb to oxidative stress [1].

What We Don't Know (but need to know)

• What are the bottlenecks in transfering energy through (and between) the photosystems?
• How is oxidative stress created from exposure to high intensity light?
• What are natural methods of controlling oxidative stress?

Important/Interesting Papers

1. Muramatsu M, Sonoike K, and Hihara Y. Mechanism of downregulation of photosystem I content under high-light conditions in the cyanobacterium Synechocystis sp. PCC 6803. Microbiology (Reading). 2009 Mar;155(Pt 3):989-996. DOI:10.1099/mic.0.024018-0 |