IGEM:Stanford/2009/Oxidative Stress

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Project Summary

Not defined yet.

What We Know

  • In high intensity light, wild type cyanobacteria downregulate Photosystem I [1].
  • The mutant pmgA cannot downregulate Photosystem I in high intensity light [1].
  • pmgA mutants initially grow well in high intensity light (better than wild type) but after 48 hours they succumb to oxidative stress [1].

What We Don't Know (but need to know)

  • What are the bottlenecks in transfering energy through (and between) the photosystems?
  • How is oxidative stress created from exposure to high intensity light?
  • What are natural methods of controlling oxidative stress?

Experiment Ideas


Important/Interesting Papers

  1. Muramatsu M, Sonoike K, and Hihara Y. Mechanism of downregulation of photosystem I content under high-light conditions in the cyanobacterium Synechocystis sp. PCC 6803. Microbiology. 2009 Mar;155(Pt 3):989-96. DOI:10.1099/mic.0.024018-0 | PubMed ID:19246769 | HubMed [muramatsu]