Haynes Lab:Notebook/Synthetic Biology and Bioinformatics for Predictable Control of Therapeutic Genes/2012/02/08

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Gene Check

  • There a couple of good "housekeeping genes" to take note of to see if we are on the right track
  • Silenced: CDKN2A and MYT1 are predicted to have good histone methylation peaks

CDKN2A.PNG CDKN2A MYT1.PNG MYT1

  • Active: GAPDH and ACTB are predicted to have low histone methylation peaks

GAPDH.PNG GAPDH ACTB.PNG ACTB

  • As it can be seen these genes show that silenced genes show significant peaks in histone methylation while active genes show little or no histone methylation peaks