Eccles:The Otago Medical School Research Society
The 184th Scientific Meeting of
The Otago Medical School Research Society
presents an invited lecture by
Professor Kurt Krause
Department of Biochemistry, University of Otago
New protein crystallography capabilities at the University
of Otago and a proposed CoRE in infectious diseases
Thursday 24th August @ 5 pm
Barnett Lecture Theatre
To be followed by refreshments
Dr. Kurt Krause is a professor of Biochemistry at the University of Otago in Dunedin, New Zealand. He
obtained his M.D. at Baylor College of Medicine in Houston, Texas in 1980. He received his M.A. and
Ph.D. in Chemistry from Harvard University in 1983 and 1986, respectively. He carried out his doctoral
research in the laboratory of Nobel Laureate William N. Lipscomb, Jr. His research areas include
structural biology of infectious diseases, structure-aided drug design, protein crystallography, X-ray
diffraction, structure and function of enzymes and proteins including antibiotic targets, redox proteins,
nucleases, luciferase, and bacterial pathogenesis factors. Dr. Krause is board certified in Internal Medicine
and is a specialist in infectious diseases. He has extensive experience in the treatment of HIV/AIDS and
tuberculosis.
Dr. Krause has over 20 years of experience in protein crystallography including purification and
crystallization of proteins, high resolution data collection, structure determination via MAD, MIR as well
as molecular replacement methods, building and refinement, and structural interpretation. In his group
there is a long-standing interest in the structure and function of drug targets, virulence factors and redox
proteins, especially those from highly pathogenic organisms. Dr. Krause also has experience in
MIC/MBC determinations in drug resistant bacteria and in mechanisms of antimicrobial resistance.
