From OpenWetWare
Jump to navigationJump to search

Outline of MIT syn bio tea talk

1) Applications of syn bio to space

photosynthetic Chassis Choice


Research Article The Genome of the Diatom Thalassiosira Pseudonana: Ecology, Evolution, and Metabolism

Fuels for space

  • Notes from speaking to David Thompson
  • Oxygen - O2 as byproduct of photosynthesis
  • Hydrogen - via the biohydrogen route
  • nitrogenase, the enzyme that fixes N2 to NH3(amonia)ozene

, as a normal part of its function it produces H2 albeit at a much slower rate than NH3, its a side reaction. but if you force the reaction in an atmosphere with zero nitrogen, then you get H2 production exclusively. (Hydrogen-2, H-2, 2H (a.k.a. Deuterium), an isotope of Hydrogen (1 proton, 1 neutron, 1 electron))


  • Deep sea bacteria that make hydrazine as a free metabolic intermediate. (Hydrazine is used as a bipropellant in combination with O2 I (DT) believe,and some of its derivatives are used in combination with other liquid rocket fuels...) is a resource for research on those particular bacteria.


A strongly alkaline crystalline compound, NHC(NH2)2, formed by the oxidation of guanine and found in the urine as a normal product of protein metabolism. It is commonly used in the organic synthesis of plastics, resins, and explosives. ( Guanine production was hypothetical, it would involve tweaking the purine biosynthetic pathway, and i think i mentioned a purine efflux pump...

making TAL for TATB production was from this paper


ammonia, formaldehyde --> hexamine (fireproofing, plastics) --> hexogen/RDX

toluene, sulfuric acid, nitric acid --> trinitrotoluene

acetone, sulfuric acid, hydrogen peroxide --> acetone Peroxide/TATP

guanine --> nitroguanidine

malonyl-CoA --> triacetic acid lactone --> LCD's

side product is phloroglucinol (can make adhesives)

ammonia, formaldehyde