Our lab is interested in transposons using an approach combining biochemistry, cell biology, bioinformatics and mathematical modelling.
Our current projects are:
- To determine the mechanism of mariner transposition
- To find the functions of a primate-specific domesticated transposases
- To engineer mariner transposons and their derivatives as gene vectors
Claeys Bouuaert C, Lipkow K, Andrews SS, Liu D, Chalmers R. The autoregulation of a eukaryotic DNA transposon. Elife. 2013 Jun 18;2:e00668.